UV-SPECTROSCOPY STUDY OF THE EFFECT OF TEMPERATURE ON HUMAN BLOOD PLATELETS
Keywords:
platelet, aggregation, receptors, temperature, UV-speclroscopy
Abstract
The structural changes of human blood platelet proteins at temperatures from 6 to 40°C have been studied by using UV-spectroscopy method. The change of platelet shape has been found at 14-18°C when heated. This fact is probably connected to a rearrangement of the cytoskeleton and actin polymerisation. The structural changes of ADP and fibrinogen receptors of the platelet plasma membrane have been observed at 18-20°C and 30-32°C, as well. It has been supposed that these changes determine the features of the dependence of ADP-induced platelet aggregation on temperature.
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Cited
How to Cite
Berest, V. P., Morozova, T. F., & Gatash, S. V. (1). UV-SPECTROSCOPY STUDY OF THE EFFECT OF TEMPERATURE ON HUMAN BLOOD PLATELETS. Biophysical Bulletin, 2(2). Retrieved from https://periodicals.karazin.ua/biophysvisnyk/article/view/2449
Section
Cell biophysics
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