Complete left bundle branch block as predictor of cardiogenic shock in patient with acute myocardial infarction on the background of diabetes mellitus type 2

  • Olena Makharynska MD, PhD,  Associate professor of department of Propaedeutics of Internal Medicine and Physical Rehabilitation, V. N. Karazin Kharkiv National University, 6, Svobody Sq., Kharkiv, Ukraine, 61108 https://orcid.org/0000-0001-5326-1587
  • Nataliia Bogun MD, Assistant of department of Propaedeutics of Internal Medicine and Physical Rehabilitation, V. N. Karazin Kharkiv National University, 6, Svobody Sq., Kharkiv, Ukraine, 61108 https://orcid.org/0000-0002-8176-8171
  • Irina Oktiabrova MD, Assistant of department of Propaedeutics of Internal Medicine and Physical Rehabilitation, V. N. Karazin Kharkiv National University, 6, Svobody Sq., Kharkiv, Ukraine, 61108 https://orcid.org/0000-0001-5083-0131
  • Эке Міракл Чиамака 4th year students (group BA – 401) of School of Medicine V.N. Karazin Kharkiv National University 6, Svobody Sq., Kharkiv, Ukraine, 61022
Keywords: left bundle branch block, acute myocardial infarction, cardiogenic shock, diabetes mellitus type 2, mechanical circulatory support

Abstract

Cardiogenic shock is the leading cause of death in patients with acute myocardial infarction, with high hospital mortality rates ∼80 %. The incidence of cardiogenic shock among myocardial infarction patients is approximately 7 %. Cardiogenic shock patients are found that pre-existing diabetes is associated with an increased risk of cardiogenic shock and it worsens outcomes, with a longer hospital stay. Cardiogenic shock develops approximately twice as often among diabetics as among nondiabetic patients with acute myocardial infarction. Diabetes mellitus and left bundle branch block are predictors of cardiogenic shock complicating acute myocardial infarction. Except for bad prognosis, left bundle branch block can be a marker of a slowly progressing, degenerative, ischemic or non-ischemic cardiac disease, affecting not only the muscle but also the heart conduction system. Immediate diagnosis and management are required. In this article, a clinical case of acute posterior myocardial infarction complicated by complete left bundle branch block and cardiogenic shock in the patient with concomitant diabetes mellitus type 2 is demonstrated.  This article emphasizes the priority of referring patients with left bundle branch block to primary percutaneous coronary intervention, usage of more specific ECG criteria for acute coronary syndrome, the role of myocardial infarction biomarker including sensitive assays for cardiac troponins, and bedside echocardiography which may improve diagnostic accuracy and result in timely intervention in such patients. This article also underlines the role of mechanical circulatory support, urgent reperfusion therapy, and strict control of glycemia in the acute phase of myocardial infarction which may contribute to clinical stability of patients with diabetes mellitus and myocardial infarction complicated by cardiogenic shock.

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Published
2020-06-24
How to Cite
Makharynska, O., Bogun, N., Oktiabrova, I., & Чиамака, Э. М. (2020). Complete left bundle branch block as predictor of cardiogenic shock in patient with acute myocardial infarction on the background of diabetes mellitus type 2. Actual Problems of Modern Medicine, (5), 27-34. https://doi.org/10.26565/2617-409X-2020-5-04