RELAXATION AND SPECTROSCOPIC MANIFESTATIONS OF HYDRATION OF POLYRIBOCYTIDYLIC ACID

  • V. A. Kashpur Institute for Radiophysics and Electronics, National Academy of Sciences of Ukraine Address: 12, Acad. Proskura St. 310085, Kharkov, Ukraine
  • M. A. Semenov Institute for Radiophysics and Electronics, National Academy of Sciences of Ukraine Address: 12, Acad. Proskura St. 310085, Kharkov, Ukraine
  • N. N. Sagaidakova Institute for Radiophysics and Electronics, National Academy of Sciences of Ukraine Address: 12, Acad. Proskura St. 310085, Kharkov, Ukraine

Abstract

Hydration and structure state of polyribocytidylic acid (poly(rC)) have been studied in solutions and humid films. The role of water in forming different structures of poly(rC) was elucidated, hi solutions, the hydration values of single-strand (pH 4.5), double-strand (pH 7.8) and disordered (pH 3.3) forms of poly(rC) were determined with a differential EHF-dielectrometer using the measurements of dielectric permittivity at wavelength7.6 mm. In humid films, distribution of water molecules on the hydration sites for these structures has been found with IR spectroscopy. Hydration models of the single and double-strand structures of poly(rC) were developed using X-ray and these data.

KEY WORDS: polycytidylic acid, hydration, infrared spectra, millimeter region, structural transitions.

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References

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Cited
How to Cite
Kashpur, V. A., Semenov, M. A., & Sagaidakova, N. N. (1). RELAXATION AND SPECTROSCOPIC MANIFESTATIONS OF HYDRATION OF POLYRIBOCYTIDYLIC ACID. Biophysical Bulletin, 3(5). Retrieved from https://periodicals.karazin.ua/biophysvisnyk/article/view/2481
Issue
Vol. 3 No. 5 (1999): Біофізичний вісник
Section
Molecular biophysics

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