Mathematical modelling of processes, defining radiosensitiveness differently oxygenation of layers of a malignant tumour's

Authors

  • V. G. Knigavko Kharkiv State Medical University Author
  • N. S. Ponomarenko Kharkiv State Medical University Author
  • E. B. Radzishevska Kharkiv State Medical University Author
  • L. V. Batyuk Institute Medical Radiology S.P.Grigorieva Author
  • N. P. Poletova Kharkiv State Medical University Author

Keywords:

mathematical modeling, radiosensitivity of tumour cells, oxygenation

Abstract

For layers of an orbicular tumor, the concept of mathematical modeling which determines its radiosensitivity was offered. Expression, which connects the survival rate of the irradiated cells to an absorbed dose X-ray or the gamma-radiation was obtained. The connection of expression parameters with oxygen concentration was analyzed and the dependence between the survival rate of tumor layers and their oxygenation was obtained.

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Author Biographies

  • V. G. Knigavko, Kharkiv State Medical University

    4 Lenin ave., Kharkiv, 61022, Ukraine

  • N. S. Ponomarenko, Kharkiv State Medical University

    4 Lenin ave., Kharkiv, 61022, Ukraine

  • E. B. Radzishevska, Kharkiv State Medical University

    4 Lenin ave., Kharkiv, 61022, Ukraine

  • L. V. Batyuk, Institute Medical Radiology S.P.Grigorieva

    82 Pyshkinskay str., Kharkiv, Ukraine

  • N. P. Poletova, Kharkiv State Medical University

    4 Lenin ave., Kharkiv, 61022, Ukraine

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Published

2008-09-29

Issue

Section

Biophysics of complex systems

How to Cite

Mathematical modelling of processes, defining radiosensitiveness differently oxygenation of layers of a malignant tumour’s. (2008). Biophysical Bulletin, 1(20). https://periodicals.karazin.ua/biophysvisnyk/article/view/1573

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