The investigation of the erythrocyte membranes hydration before and after radiotherapy
Keywords:
erythrocytes, erythrocyte membranes, the frequency of the dielectric relaxation, dielectric permittivity, hydration, temperature, microwave dielectric method
Abstract
The temperature dependence of the frequency of water molecules dielectric relaxation and hydration in the erythrocytes and erythrocyte membranes of donors and oncological patients within the temperature range of 1-47°С has been studied by the microwave dielectric method. It has been shown that the structural changes in the erythrocyte membranes of the oncological patients within the temperature range 8-15°C are accompanied by the change of the membrane permeability for the water molecules and the relation of free and bound water. The increasing of the erythrocyte membranes hydration at cancer leads to extension of hydrated layer and slowing down of water diffusion through a membrane. The structural transition is preceded by membrane dehydration of the oncological patients. The result is the decrease of water mobility in erythrocyte in comparison with water mobility in the environmental physiological solution.
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References
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Gordon D. Organicheskaia khimiia rastvorov elektrolitov. M.:Mir; 1979. 712p. (in Russian)
Chernitckii EA, Vorobei AV. Struktura i funktcii eritrotcitarnykh membran. Minsk:Nauka i tekhnika; 1981. 216p. (in Russian)
Borisova AG, Oleinik EK. Klinich. lab. diagn. 2001;5:14-6. (in Russian)
Zhuravlev AK, Murashko VV. Biul. eksperimentalnoi biologii i meditciny. 1984;98(11):596-8. (in Russian)
Zabelinskii SA, Chebotareva MA, Krivchenko AI. Zhurn. evoliutc. biokhim. 1996;32(6):722-34. (in Russian)
Shilovtceva AS. O sootnoshenii osnovnykh elektrolitov v dinamike razvitiia nekotorykh zlokachestvennykh novoobrazovanii. Kuibyshev. 1971. 32p. (in Russian)
Lang F, Busch GL, Ritter M. Physiological reviews. 1998;78(1):132-45.
Yarbro JW, Boornstein RS. Oncologic Emergencies. New York, 1981.
Popovskaia TN. Vestn. mor. med. Odessa; 2000. 70-5p. (in Russian)
Bardychev MS, Katcalap SN. Vopr. onkologii. 1995;45(2):99. (in Russian)
Hall EJ. Radiobiology for the radiologist. 1994. 167p.
Vorobev EI, Stepanov RP. Ioniziruiushchee izluchenie i krovenosnye sosudy. M.:Enegoatomizdat; 1985. 296p. (in Russian)
Dvoretckii AI, Ananeva TV, Kulikov IA, Egorova EG. Neirotransmitternaia moduliatciia ionnogo gomeostaza v kletkakh golovnogo mozga pri ridiatcionnykh vozdeistviiakh. Kiev; 2001. 167p. (in Russian)
Sorokina ZA. Sostoianie Kaliia, natriia i vody v tcitoplazme kletok. Kiev:Nauk. dumka;1978. 212p. (in Russian)
Antonchenk VIa. Mikroskopichekaia teoriia vody v porakh membran. Kiev:Nauk. dumka;1983. 160p. (in Russian)
Morariu VV, Benga Ch. Membrance Process. New York:E. A; 1984.p.121-39.
Verbavatz JM, Brown D, Sabolic I. Journal of Cell Biology. 1993;123(3):18.
Dix JA, Solomon AK. Biochim. Biophys. Acta. 1984;773(2):219-30.
Pliquett U, Pliquett F. Phys. Chem. Biol. &Med. 1996;2:11-9.
Farrant J, Woolgar AE. Ibid. 1972;9(1):9.
Moiseev VA, Mezhidov SKh, Nadrid OA. Biofizika. 1989;34(6):993-6. (in Russian)
Bolis LS, Khoffman DF, Lif A. Membrany i bolezn. M.:Meditcina; 1980. 408p. (in Russian)
Berest VP, Gatash SV, Nikolov OT. Vestnik KhDU. 1999;3(1):92-5. (in Russian)
Shchegoleva TIu, Bakhova LK. Biofizika. 1985;30(4):358-9. (in Russian)
Batiuk LV, Gatash SV, Gorobchenko OA, Nikolov OT. Vestnik Kharkovskogo universiteta. 2002;1(10):54-7. (in Russian)
Nikolov OT, Zhiliakova TA. Zhurn. fiz. khim. 1991;65(5):1312-16. (in Russian)
Glesston S, Leider K, Eiring G. Teoriia absoliutnykh skorostei reaktcii. M.:IIL; 1948. (in Russian)
Zhiliakova TA, Nikolov OT, Maleev VIa. Zhurn. fiz. khim. 1993;67(7):1396-400. (in Russian)
Minetti M, Ceccarini M, Di Stasi AM. J. Cell Biochem. 1984;25(2):73-86.
Gordon LM, Mobley PW. J. Membr. Biol. 1984;79(1):75-86.
Forte T, Leto TL, Minetti M, Marches VT. Biochemistry. 1985;24(27):7876-80.
Marcelja S, Wolfe J. BBA. 1979;557(1):24-32.
Minetti N, Ceccarini M. J. Cell Biochem. 1982;19(1):59-77.
Bennett V. Biochem. Biophys. Acta. 1989;988(1):107-21.
Finenan Dzh, Kolmen R, Mitchell R. Membrany i ikh funktcii v kletke. 1977;78-107. (in Russian)
Grekh IF, Zeldovich DR, Bognibov EA. Med. radiol. 1964;9(2):52-6. (in Russian)
Badzhinian SA, Kazarian PA, Akopov SE, Saarian AV. Rad. biol. radioekol. 1995;35(3):364-9. (in Russian)
Potulnitckaia LN. Ugnetenie gemopoeza pri luchevoi terapii nekotorykh zlokachesttvennykh novoobrazovanii i ego vosstanovlenie putem automielotransplantatcii. Porazhenie i vosstanovlenie krovetvoreniia pri ostroi luchevoi bolezni. Moskva; 1990. 66p. (in Russian)
Kavutckii RE. Diagnostika i lechenie zlokachestvennykh zabolevanii. Naukova dumka; 1979. 180p. (in Russian)
Kiseleva ES. Luchevaia terapiia v kombinirovannom i kompleksnom. Kombinirovanie i kompleksnoe lechenie blnykh zlokachestvennymi opukholiami. Moskva;1989. 22-40p. (in Russian)
Bala IuM, Beloshevskii VA. Gematol. i transfuziol. 1987;32(4):32-8. (in Russian)
Gordon D. Organicheskaia khimiia rastvorov elektrolitov. M.:Mir; 1979. 712p. (in Russian)
Chernitckii EA, Vorobei AV. Struktura i funktcii eritrotcitarnykh membran. Minsk:Nauka i tekhnika; 1981. 216p. (in Russian)
Borisova AG, Oleinik EK. Klinich. lab. diagn. 2001;5:14-6. (in Russian)
Zhuravlev AK, Murashko VV. Biul. eksperimentalnoi biologii i meditciny. 1984;98(11):596-8. (in Russian)
Zabelinskii SA, Chebotareva MA, Krivchenko AI. Zhurn. evoliutc. biokhim. 1996;32(6):722-34. (in Russian)
Published
2018-06-25
Cited
How to Cite
Batyuk, L. V., Gatash, S. V., Gorobchenko, O. A., & Nikolov, O. T. (2018). The investigation of the erythrocyte membranes hydration before and after radiotherapy. Biophysical Bulletin, 2(13), 72-77. Retrieved from https://periodicals.karazin.ua/biophysvisnyk/article/view/12513
Section
Cell biophysics
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