Software to simulate osmotic behavior of a single erythrocyte
Keywords:
erythrocyte, modeling, software
Abstract
This paper introduces the software to simulate the osmotic relaxation behavior of single erythrocyte. The
application calculates changes in membrane potential, cell volume, water flux and concentration of
penetrating ions in response to snap changes in the composition of external medium. Developed
application could be used as standalone software or integrated into in silico cell model.
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References
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4. Wang D. Single cell analysis: the new frontier in 'omics' / D. Wang, S. Bodovitz // Trends Biotechnol. – 2010. – V. 28, N 6. – P. 281-290.
5. Ideker T. Boosting signal-to-noise in complex biology: prior knowledge is power / T.Ideker, J. Dutkowski, L. Hood // Cell. – 2011. – V. 144, N 6. – P. 860-863.
6. Distributions of rheological parameters in populations of human erythrocytes / I.L. Lisovskaya, E.S. Shurkhina, E.E. Yakovenko, [et al.] // Biorheology. – 1999. – V. 36, N 4. – P. 299-309.
7. Kak reguliruetsja ob#jom jeritrocita, ili chto mogut i chego ne mogut matematicheskie modeli v biologii / F.I. Ataullahanov, N.O. Korunova, I.S. Spiridonov, [i dr.] // Biologicheskie membrany. – 2009. – T. 26, № 3. - S. 163-179.
8. Dynamic simulation of the human red blood cell metabolic network / N. Jamshidi, J.S. Edwards, T. Fahland, [et al.] // Bioinformatics. – 2001. – V. 17, №3. – P. 286-297.
9. Description and analysis of metabolic connectivity and dynamics in the human red blood cell / K. Kauffman, J.D. Pajerowski, N. Jamshidi, [et al.] // Biophysical Journal. – 2002. – V. 83. – P. 646-662.
10. Lew V.L. Volume, pH, and ion-content regulation in human red cells: analysis of transient behavior with an integrated model / V.L. Lew, R.M. Bookchin // J. Membr. Biol. – 1986. – V. 92. – P. 57–74.
11. Matematicheskaja model' reguljacii ob#ema jeritrocitov / I.A. Moroz, F.I. Ataullahanov, A.B. Kijatkin, [i dr.] // Biologicheskie membrany. – 1989. – T. 6. – S. 409-419.
12. Jamshidi N. Systems biology of the human red blood cell / N. Jamshidi, B.Ø. Palsson // Blood Cells Mol Dis. – 2006. V. 36, N 2. – P. 239-247.
Cited
How to Cite
Shevchenko, E. E., & Berest, V. P. (1). Software to simulate osmotic behavior of a single erythrocyte. Biophysical Bulletin, 2(27). Retrieved from https://periodicals.karazin.ua/biophysvisnyk/article/view/2544
Section
Methods of biophysical investigations
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