INFLUENCE OF γ-IRRADIATION ON STATE OF DNA ION-HYDRATION SHELL
Keywords:
DNA, electrophoresisAbstract
The effect of γ-radiation on the state of DNA hydration shell has been investigated. The changes of dielectric permittivity of DNA aqueous solutions irradiated at doses 19, 370, and 1650 Gy have been studied using the differential dielectrometric method. The DNA state was checked by conductance-measuring and electrophoresis methods. Some noticeable changes of DNA hydration at 370 and 1650 Gy have been found. It has been shown that the effects revealed are due to the breach of water backbone structure arising from double helix reconstructions which appear to be a result of radiation deoxyribosyl lesions and also to the appearance of DNA radiation-altered bases.
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Action of physical agents on biological objects
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How to Cite
INFLUENCE OF γ-IRRADIATION ON STATE OF DNA ION-HYDRATION SHELL. (2015). Biophysical Bulletin, 1(1). https://periodicals.karazin.ua/biophysvisnyk/article/view/2059
