Cardiolipin effect on the lipid bilayer structure: pyrene excimerization study
Keywords:
liposomes, pyrene excimer formation, cardiolipin, lipid bilayer structure, free volume
Abstract
The influence of cardiolipin (CL) on the structural state of model membranes has been examined using the pyrene epimerization technique. The excimer-to-monomer ratio decreased by 11 % as CL content increased from 0 to 10 mol % suggesting that CL can induce bilayer condensation. At higher CL concentrations (20 and 40 mol %) excimer-to-monomer ratio tended to increase is indicative of the reduced lipid packing density. The biological role of CL is discussed.
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References
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5. Bartlett G. // J. Biol. Chem. 1959. V.234. P. 466-468.
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7. Blackwell M.F., Gounaris K., Barber J. // Biochim. Biophys. Acta. 1986. V. 858. P. 221-234.
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Published
2005-06-06
Cited
How to Cite
Ioffe, V., Gorbenko, G., & Domanov, Y. (2005). Cardiolipin effect on the lipid bilayer structure: pyrene excimerization study. Biophysical Bulletin, 1(15), 104-107. Retrieved from https://periodicals.karazin.ua/biophysvisnyk/article/view/18288
Section
Methods of biophysical investigations
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