Simulation of effects of γ-aminobutyric acid introduced into NO-synthesize cardiovascular neurons of medulla rats
Keywords:
medulla rats, NO-synthesize cardiovascular neurons, arterial pressure, simulation
Abstract
Time dependence of system arterial pressure of rats after γ-aminobutyric acid injections into the cardiovascular neurons of their medulla is studied theoretically
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References
De Vente J, Hopkins DA, Maiierink-Van LM. Distribution of nitric oxide synthase and nitric oxide receptive cyclic GMP-producing structures in the rat brain. Neuroscience. 1998;87:207-41
Gai WP, Messenger JP, Iu YH. Nitric oxide-synthasizing neurons in the central nervous subnucleus of the nucleus tractus solitarius provide a major innervation of the rostral nucleus ambiguus in the rabbit. J.Comp.Neurol. 1995;357:348-61.
Vincent SR, Kimura H. Histochemical mapping of nitric oxide synthase in the rat brain. Neuroscience. 1992;46:755-84.
Zanzinger J, Czachurski J, Seller H. Effects of nitric oxide on sympathetic baroreflex transmission in the nucleus tractus solitarii and caudal ventrolateral medulla in cats. Ibid. 1995;197:199-202.
Sakai K, Hirooka Y, Matsuo I. Overexpression of eNOS in NTS causes hypotension and bradycardia in vivo. Hypertension. 2000;36:1023-8.
Paxinos G, Watson C. The rat brain in stereotaxic coordinates. N.J.:Academic Press; 1982. p. 83.
Shapoval LM,Sagpch VF, Pobigailo SS, Stepanenko LG, Ermolinska NV. Rol oksydu azotu v realizatcii efektyv intrabulbarno vvedenoii y-aminomaslianoii kysloty na systemu krovoobigu. Fiziol.zhurn. 2005;51(1):43-50. (in Ukrainian)
Amano M, Kubo T. Involvement of both GAB Aa and GABAb receptors in tonic inhibitory control of blood pressure at rostral ventrolateral medulla of the rat. Naunyn Schemiedebergs Arch. Pharnacol. 1993;348:146-53
Blessing WW. Depressor neurones in rabbit caudal medulla act via GABA receptors in rostral medulla. Amer. J. Physiol. 1988;23:H786-92
Kagiyama S, Tsuchihashi T, Abe I, Fujishima M. Cardiovascular effects of nitric oxide in the rostral ventrolateral medulla of rats. Brain Res. 1997;757:155-158.
Meeley MP, Ruggiero DA, Ishitsuka T, Reis DJ. Intrinsic g-aminobutyric acid neurons in the nucleus of the solitary tract and rostral ventrolateral medulla of the rat: immunocytochemical and biological study. Neurosci.Lett. 1985;58:83-9.
Martins-Pinge MC, Baraldi-Passy I, Lopes OU. Excitatory effects of nitric oxide within the rostral ventrolateral medulla of freely moving rats. Hypertension. 1997;30:704-7.
Ying JP, Qian LG, Peng LL. GABa receptors in the rostral ventrolateral medulla mediate the depressor response induced by stimulation of the greater aplanchnic nerve afferent fibres in rats. Neurosci. Lett. 1998;249:95-8.
Kishi T, Hirooka Y, Sakai K. Overexpression of eNOS in the RVLM causes hypertension and drady-cardia via GABA release. Hypertension. 2001;38:896-904.
Gai WP, Messenger JP, Iu YH. Nitric oxide-synthasizing neurons in the central nervous subnucleus of the nucleus tractus solitarius provide a major innervation of the rostral nucleus ambiguus in the rabbit. J.Comp.Neurol. 1995;357:348-61.
Vincent SR, Kimura H. Histochemical mapping of nitric oxide synthase in the rat brain. Neuroscience. 1992;46:755-84.
Zanzinger J, Czachurski J, Seller H. Effects of nitric oxide on sympathetic baroreflex transmission in the nucleus tractus solitarii and caudal ventrolateral medulla in cats. Ibid. 1995;197:199-202.
Sakai K, Hirooka Y, Matsuo I. Overexpression of eNOS in NTS causes hypotension and bradycardia in vivo. Hypertension. 2000;36:1023-8.
Paxinos G, Watson C. The rat brain in stereotaxic coordinates. N.J.:Academic Press; 1982. p. 83.
Shapoval LM,Sagpch VF, Pobigailo SS, Stepanenko LG, Ermolinska NV. Rol oksydu azotu v realizatcii efektyv intrabulbarno vvedenoii y-aminomaslianoii kysloty na systemu krovoobigu. Fiziol.zhurn. 2005;51(1):43-50. (in Ukrainian)
Amano M, Kubo T. Involvement of both GAB Aa and GABAb receptors in tonic inhibitory control of blood pressure at rostral ventrolateral medulla of the rat. Naunyn Schemiedebergs Arch. Pharnacol. 1993;348:146-53
Blessing WW. Depressor neurones in rabbit caudal medulla act via GABA receptors in rostral medulla. Amer. J. Physiol. 1988;23:H786-92
Kagiyama S, Tsuchihashi T, Abe I, Fujishima M. Cardiovascular effects of nitric oxide in the rostral ventrolateral medulla of rats. Brain Res. 1997;757:155-158.
Meeley MP, Ruggiero DA, Ishitsuka T, Reis DJ. Intrinsic g-aminobutyric acid neurons in the nucleus of the solitary tract and rostral ventrolateral medulla of the rat: immunocytochemical and biological study. Neurosci.Lett. 1985;58:83-9.
Martins-Pinge MC, Baraldi-Passy I, Lopes OU. Excitatory effects of nitric oxide within the rostral ventrolateral medulla of freely moving rats. Hypertension. 1997;30:704-7.
Ying JP, Qian LG, Peng LL. GABa receptors in the rostral ventrolateral medulla mediate the depressor response induced by stimulation of the greater aplanchnic nerve afferent fibres in rats. Neurosci. Lett. 1998;249:95-8.
Kishi T, Hirooka Y, Sakai K. Overexpression of eNOS in the RVLM causes hypertension and drady-cardia via GABA release. Hypertension. 2001;38:896-904.
Published
2007-06-05
Cited
How to Cite
Radchenko, N. V., Shapoval, L. M., Davydovska, T. L., & Prylutskyy, Y. I. (2007). Simulation of effects of γ-aminobutyric acid introduced into NO-synthesize cardiovascular neurons of medulla rats. Biophysical Bulletin, 1(18), 69-72. Retrieved from https://periodicals.karazin.ua/biophysvisnyk/article/view/12624
Section
Biophysics of complex systems
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