Creation of cornea biograft

  • А. С. Кавеліна
Keywords: limbal stem cells; amniotic membrane

Abstract

In recent years, the transplantation of cultured stem cells is considered the most promising method that allows influencing the process of human tissue reparation. Ophthalmologists are studying the possibility of introducing the new technology called ex vivo cultivation of epithelial stem cells to clinic. The technology enables to avoid possible complications connected with limbal autograft transplantation. Different researches by means of methods in vitro and in vivo demonstrated that amniotic membrane can be successfully used as a substrate for epithelial stem cells cultivation and their further application in the treatment of severe ocular surface disease. Peculiarities of the tissue structure and functions of amniotic membrane define the number of characters that can attract researchers and clinicians to use limbal and conjunctival epithelial covering in the treatment of corneal disease.

Downloads

Download data is not yet available.

References

Gorgiladze T.W., Ivanovskaya Ye.V. Keratoplasty as a method of rehabilitation of patients with corneal cataracts // Proc. Scientific and practical. conf. "Pathology of the optical media of the eye." – Ashgabat, 1992. – P. 33–34. (in Russian)

Grin V.K., Popandopulo A.G., Kavelina G.S. et al. Method for production of cultured limbal cells. Patent of Ukraine №65507. 12.12.2011. (in Ukrainian)

Demin Y.U, Limar I.L., Strona V.I. Preliminary results of the use of cryopreserved amnion in the treatment of diseases of the cornea // Materials of the X Congress of ophthalmologists of Ukraine. – Odessa, 2002. – P.30. (in Ukrainian)

Drozhzhina G.I., Ivanova O.N., Gaydamaka T.B. Model of neurotrophic keratitis. Patent of Ukraine. 2011. Priority reference №201106827. (in Ukrainian)

Kasparov A.A., Trufanov S.V. Using canned amniotic membrane for surface reconstruction of anterior segment // Bulletin Ophthalmology. – 2003. – №3. – P. 45–47. (in Russian)

Kasparov E.A. Treatment of recurrent corneal erosion // Bulletin of Ophthalmology. – 2009. – №3. – P. 55–57. (in Russian)

Popandopulo A.G., Kavelina G.S., Ivanova O.M, Drozhzhina G.I. Method of producing a monolayer of cultured limbal stem cells and corneal epithelium cells on amniotic membrane. Pat. Ukraine №87174 A61F9 / 00. Publish. 27.01.2014. Bull. №2. (in Ukrainian)

Novitsky I.Y. Amniotic membrane transplantation place in the treatment of corneal diseases accompanied by her neovascularization // Bulletin of Ophthalmology. – 2003. – №6. – P. 9–11. (in Russian)

Pasechnikova N.V., Ivanov O.N., Drozhzhina G.I. et al. The influence of culture on limbal epithelial cell regeneration processes in experimental corneal neurotrophic keratopathy // Filatov’s readings. Proceedings of the conference, dedicated to the 75th anniversary of the V.P.Filatov Institute. – Odessa, 2011. – P. 29–30. (in Ukrainian)

Azuara-Blanco A., Pillai C.T., Sarhan A., Dua H.S. Amniotic membrane transplantation for ocular surface reconstruction // Invest. Ophthalmol. Vis. Sci. – 1998. – Vol.39. – P.428.

Bonini S., Rama P., Olzi D., Lambiase A. Neurotrophic keratitis // Eye. – 2003. – Vol.17. – P. 989–995.

Davis E., Dohlman C. Neurotrophic keratitis // Int. Ophthalmol Clin. – 2001. – Vol.41. – P. 1–11.

Dua H.S, Gomes G., King A. The amniotic membrane in ophthalmology // Surv. Ophthalmol. – 2004. – Vol.49 (1). – Р. 51–77.

Francisco C.F. Amniotic membrane transplantation in ophthalmology // Focus. – Newcastle upon Tyne, 2000. – P.16.

Friend J., Kinoshita S., Thoft R.A. et al. Corneal epithelial cell cultures on stroma carriers // Invest. Ophthalmol. Vis. Sci. – 1982. – Vol.23. – P.41–49.

Kim J.C., Tseng S.C.G. Transplantation of preserved human amniotic membrane for surface reconstruction in severly damaged rabbit corneas // Cornea. – 1995. – Vol.14. – P. 473–484.

Koizumi N., Inatomi T., Quantock A.J. et al. Amniotic membrane as a substrate for cultivating limbal epithelial cells for autologous transplantation in rabbits // Cornea. – 2000. – Vol.19. – P. 65–71.

Koizumi N., Inatomi T., Suzuki T. Cultivated epithetial stem cell transplantation in ocular surface disorders // Ophthalmology. – 2001. – Vol.108 (9). – P. 1569–1574.

Lambiase A., Rama P., Aloe L., Bonini S. Management of neurotrophic keratopathy // Curr. Opin. Ophthalmol. – 1999. – Vol.10. – P. 270–276.

Lee S.H, Tseng S.C.G. Amniotic membrane transplantation for persistent epithelial defects with ulceration // Am. J. Ophthalmol. – 1997. – Vol.123. – P. 303–312.

Mackie I. Neuroparalytic keratitis // In: F.Fraunfelder, F.H.Roy, S.M.Meyer Current ocular therapy. – Philadelphia: WB Saunders, 1995. – P. 452–454.

Meller D., Pires R., Mack R., Figueiredo F. Amniotic membrane transplantation for acute chemical or thermal burns // Ophthalmology. – 2000. – Vol.107. – P. 980–990.

Pushker N., Dada T., Vajpayee R.B. et al. Neurotrophic keratopathy // CLAO J. – 2000. – Vol.27. – P. 100–107.

Sato H., Shimazaki J., Shinozaki K., Tsubota K. Role of growth factors for ocular surface reconstruction after amniotic membrane transplantation // Invest. Ophthalmol. Vis. Sci. – 1998. – Vol.39. – S.428.

Solomon A., Espana E., Tseng S. Amniotic membrane transplantation for reconstruction of the conjunctival fornices // Ophthalmology. – 2003. – Vol.110 (1). – P. 93–100.

Tsai R., Li L., Chen I. Reconstruction of damaged corneas by transplantation of autologous limbal epithelial cells // N. Eng. J. Med. – 2000. – Vol.343. – P. 86–93.

Tseng S.G, Tsubota K. Amniotic membrane transplantation for ocular surface reconstruction // In: Ocular surface diseases: medical and surgical management, ed. E.Holland and M.Mannis. – Springer, 2001. – P. 3–15.

Von Versen-Hoynck F., Hesselbarth U., Moller D. Application of sterilised human amnion for reconstruction of the ocular surface // Cell and Tissue Banking. – 2004. – Vol.5. – P. 57–65.

Published
2014-02-25
Cited
How to Cite
Кавеліна, А. С. (2014). Creation of cornea biograft. The Journal of V.N.Karazin Kharkiv National University. Series «Biology», 21(1112), 7-12. Retrieved from https://periodicals.karazin.ua/biology/article/view/13967
Section
BIOTECHNOLOGY