PROGNOSTIC MODEL TO DETECT COMPLICATIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME

  • M. P. Kopytsya
  • N. V. Tytarenko
  • N. V. Bila
  • O. L. Oparin

Анотація

The aim of this study was to define the utility of the measurement N-terminal pro-brain natriuretic peptide (NTproBNP) and other clinical and biochemical markers to predict adverse events (death, stroke, unstable

angina, re-infarction, or necessity of revascularization at 1 year in patients with acute coronary syndrome
(ACS). Parameters with significant differences in patients with and without complications were taken for ana­ly­sis: age, heart rate (HR) at admission, levels of hemoglobin and NTproBNP. Curves of sensitivity and spe­ci­fi­city were used based on the method of ROC analysis and cut-off values were chosen for each variable. Ball scoring was performed for each parameter regard to the cut-off value and a scale for calculating the summarized diagnostic coefficient (DC) by the method of Gubler was offered. A multimarker approach includ­ed on NTproBNP, hemoglobin, HR at admission and age and the summation of balls based on offered sca­le and calculating DC provides in­formation in terms of ACS prognosis at 1 year, with a worse outcome for those with diagnostic coefficient has negative value (sensitivity 87,5 % and specificity 75,6 %). 

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Посилання

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Як цитувати
Kopytsya, M. P., Tytarenko, N. V., Bila, N. V., & Oparin, O. L. (1). PROGNOSTIC MODEL TO DETECT COMPLICATIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME. Вісник Харківського національного університету імені В. Н. Каразіна. Серія «Медицина», (24), 23-31. вилучено із https://periodicals.karazin.ua/medicine/article/view/6704
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Розділ
Clinical Research

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