The influence of quercetin on dielectric properties of insulinresistant rats blood components
Abstract
This work is devoted to the study of the influence of quercetin on dielectric properties of insulin-resistant rat blood components provided deficiency of estrogens. Estrogens deficiency was initiated by two-sided ovariectomy at the light ether narcosis. For the investigation were chosen blood plasma and serum of intact and pathology rats of the Wister population. Dielectric properties of models under consideration were measured by the VHF-electrometry method at the frequency of 9.2 GHz. The values of the real part ε' of the complex permittivity of the blood plasma and serum of intact and ovariectomy rats with different diets were obtained. It was shown the decrease of the ε' for the blood serum of the ovariectomy rats is caused by accumulation in its products of oxidation. The differences in the real part of the complex permittivity of serum and plasma undiluted and diluted by the physiological solution were calculated. The decrease in the difference between permittivity of diluted and undiluted plasma with deficiency of estrogens compared to control was revealed.
Downloads
References
Park S.M., Park C.H., Wha J.D., Choi S.B. A high carbohydrate diet induces insulin
resistance through decreased glucose utilization in ovariectomized rats // Korean J.
Intern. Med. – 2004. – Vol. 19, No. 2. – P. 87-92.
Фармакотерапия СД 2 типа [Электронный ресурс]: Кафедра эндокринологии
Института общей практики – семейной медицины (г. Киев), - Режим доступа:
Сhttp://www.endo.com.ua/diabetes.files/diabetes_treatm_tabl.htm
Low dose of flavonoid in food lowers heart disease risk [Электронный ресурс]:
Institute of food research, - Режим доступа:
http://www.ifr.ac.uk/Media/NewsReleases/071030Quercetin.html
Эффективность водорастворимой формы кверцетина (Корвитина) при лечении
острого коронарного синдрома с элевацией сегмента ST [Электронный ресурс]:
Медицинская газета «Здоров’я України», - Режим доступа: http://www.healthua.com/articles/671.html
Влияние биофлавоноидов на биохимические показатели сыворотки крови крыс с
экспериментальным сахарным диабетом 2-го типа [Электронный ресурс]:
Міжнародний ендокринологічний журнал, - Режим доступа:
http://endocrinology.mif-ua.com/archive/issue-3389/article-3395
Кровь [Электронный ресурс]: Лаборатория Пространств, - Режим доступа:
http://www.galactic.org.ua/clovo/f_k2.htm
Hacl E.V., Gatash S.V., Nikolov O.T. Using UHF-dielectrometry to study protein
structural transitions. // J. Biochem. Biophys. Methods. – 2005. – V. 63, No. 5052. –
P. 137-148.
Кост Е.А. Справочник по клиническим лабораторным методам исследования. –
М., 1975. – 384 с.
Николов О.Т., Жилякова Т.А Измерение комплексной диэлектрической
проницаемости жидких диэлектриков с большими потерями // Журнал
физической химии. – 1991. – Т.65, №5. – C. 1417-1420.
Kankofer M., Radzki R.P., Bieńko M., Albera E. Anti-oxidative/oxidative status of rat
liver after ovariectomy // J. Vet. Med. A Physiol. Pathol. Clin. Med. – 2007. – Vol. 54,
№ 5. – P. 225-229.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
