Textures of BSA films with iron and copper ions
Keywords:
solution, film, texture, biopolymer, fractals, biologically active substances
Abstract
Analysis of the patterns on the dried films of biological fluids is a promising avenue of medical diagnostics and biosensors development. The aim of this work was to study the effect of iron and copper ions on the quantitative characteristics of textures and zigzag patterns (Z-structures) observed on the films of saline solutions of bovine serum albumin (BSA). In the experiment, 0.5 mg/ml BSA, 20 mM/l NaCl, 0.05 mM/l CuCl2 and 0.2÷0.05 mM/l FeCl3 were used. For textures, the area and fractal dimension were estimated, and for zigzag patterns, area and the specific length of the Z-structures were estimated. The effect of iron and copper ions on the geometrical parameters of Z-structures was analyzed. Spatial distributions of the fractal dimension of texture and the specific length of Z-structures were analyzed. It was shown that using the product of all four parameters increases the sensitivity of the method compared to using only one of the parameters. The method can be used in pharmacology and medical biochemistry for screening drugs and chemical compounds by their degree of influence on biopolymers.Downloads
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10. Interaction of DNA with silver nanoparticles / G.M. Glibitskiy, V.V. Jelali, M.O. Semenov [et al.] // Ukr J Phys. – 2012. – V. 57 (7). – P. 695–699.
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13. Modeling of spatial–temporal distribution of the components in the drying sessile droplet of biological fluid / Yu.Yu. Tarasevich, I.V. Vodolazskaya, O.P. Bondarenko // Colloids and Surfaces A: Physicochem. Eng. Aspects. – 2013. – V. 432. – P. 99–103.
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15. Sessile nanofluid droplet drying / X. Zhong, A. Crivoi, F. Duan // Adv Colloid Interface Sci. – 2015. – V. 217. – P. 13–30.
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Cited
How to Cite
Glibitskiy, D. M., Glibitskiy, G. M., Semenov, M. A., & Shestopalova, A. V. (1). Textures of BSA films with iron and copper ions. Biophysical Bulletin, 1(35), 21-27. https://doi.org/10.26565/2075-3810-2016-35-03
Section
Molecular biophysics
Copyright (c) 2016 Glibitskiy D.M., Glibitskiy G.M., Semenov M.A., Shestopalova A.V.
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