Spectroscopic study of interactions between polymethine dyes and liposomes in aqueous solutions
Keywords:
polymethine dyes, liposome, binding constant, intermolecular interaction, thermodynamics parameters
Abstract
Interaction between cationic polymethine dyes 3,3'-dioctadecyloxacarbocyanine perchlorate (DiO), 1,1’-
dioctadecyl-3,3,3’,3’-tetramethylindocarbocyanine perchlorate (DiI), 1,1’-dioctadecyl-3,3,3’,3’-
tetramethylindodicarbocyanine perchlorate (DiD) and zwitterionic liposomes of L-α -Phosphatidylcholine
from egg yolk (PC) has been studied by spectroscopic method. Analyzing changes in the dye absorption
spectra under the variation of PC concentration and using Scott equation, binding constants (Kc) and
thermodynamic parameters ( ΔG 0 , ΔH 0 и ΔS 0 ) of ―dye-to-liposome‖ complex formation have been
calculated. It has been shown that the complex formation is spontaneous and energetically favorable
process associated with the change in dye aggregate state from associates to monomer form. The main
contribution in complex formation process belongs to hydrophobic and Van der Waals forces, while the
contribution of electrostatic interactions is negligible.
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References
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5. Newly synthesized fluorescent probes, their characteristics and behavior in proliferating cultures / E.I. Goncharuk, I.A. Borovoy, E.V. Pavlovich, [et al.] // Biopolymers and Cell. – 2009. – V.25, № 6. – P. 484-490.
6. Waggoner A.S. Dye indicators of membrane potential / A.S. Waggoner // Ann. Rev. Biophys. Bioeng. – 1979. – V. 8. – 47-68.
7. Generation of a proton motive force by the excretion of metal-phosphate in the polyphosphate-accumulating acinetobacter johnsonii strain 210A / H.W van Veen , T. Abee , G.J Kortstee, [et al.] // J. Biol. Chem. – 1994. – V.269, №47. – P. 29509-29514.
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9. Multiparameter flow cytometric analysis of antibiotic effects on membrane potential, membrane permeability, and bacterial counts of staphylococcus aureus and micrococcus luteus / D. Novo, N.G. Perlmutter, R.H. Hunt, H.M. Shapiro // Antimicrobial Agents and Chemotherapy. – 2000. – V. 44, №4. – P. 827-834.
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11. Wiegand D.H. Spectroscopic and Fluorometric Characterization of Oxacyanine Dyes in Water and Nitrobenzene / D. H. Wiegand, P. Vanýsek // Appl. Spectrosc. – 1988. – V. 42. – P. 958-961.
12. Koti A.S.R. Cyanine induced aggregation in meso-tetrakis(4-sulfonatophenyl)porphyrin anions / A.S.R. Koti, N. Periasamy // Journal of Material Chemistry. – 2002. – V. 12, №8. – P. 2312-2317.
13. Studies on the mechanism by which cyanine dyes measure membrane potential in red blood cells and phosphatidylcholine vesicles / P.J. Sims, A.S. Waggoner, C.H. Wang, J.F. Hoffman // Biochemistry. – 1974. – V. 13. – P.3315-3330.
14. Block copolymer nanostructures / T. Smart, H. Lomas, M. Massignani, [et al.] //NanoToday. – 2008. – V. 3, №3-4. – P. 38-46.
15. Liposomal drug delivery, a novel approach: PLARosomes / A. Kozubek, J. Gubernator, E. Przeworska, M. Stasiuk //Acta Biochimica Polonica. – 2000. – V. 47, №3. –P. 639-649.
16. Liposomal drug delivery systems – clininal applications / P. Goyal, K. Goyal, S.G.V. Kumar, [et al.] // Acta Pharm. – 2005. – V. 55. – P. 1-25.
17. Petros R.A. Strategies in the design of nanoparticles for therapeutic application / R.A. Petros, J.M. DeSimone //Nature Reviews Drug Discovery. – 2010. – V. 9. – P. 615-627.
18. Nishiyama N. Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery / N.Nishiyama, K.Kataoka // Pharmacology and Therapeutics. – 2006. – V. 112. – P. 630-648.
19. Liposomes: a practical approach. – 2nd ed. – [ed. by V. Torchilin and V. Weissig]. – Oxford: Oxford Univ. Press. – 2003. – 396 p.
20. Ефимова С.Л. Спектрально-люминесцентные свойства 1,1-диоктадецил-3,3’,3’-тетраметилиндодикарбоцианинперхлората в бинарных растворах / С.Л. Ефимова, Ю.В. Малюкин, К. Кемнитц // Журн. прикл. спектр. – 2001. – T. 68. – С. 569-572. /Efimova S.L. Spektral'no-ljuminescentnye svojstva 1,1-dioktadecil-3,3’,3’-tetrametilindodikarbocianinperhlorata v binarnyh rastvorah / S.L. Efimova, Ju.V. Maljukin, K. Kemnitc // Zhurn. prikl. spektr. – 2001. – T. 68. – S. 569-572./
21. Malyukin Yu.V. Spectroscopy of intermolecular interaction in the system: dye-sodium dodecylsulphate micelle / Yu.V. Malyukin, S.L. Efimova, K. Kemnitz // J. Lumin. – 2001. - 94-95. – P. 239-242.
22. Безызлучательный перенос энергии в композициях карбоцианиновых красителей в нанообъеме мицеллы ПАВ / С.Л. Ефимова, А.В. Сорокин, А.Н. Лебеденко, [и др.] // Журн. прикл. спектр. – 2006. – Т. 73. – С. 152-157. /Bezyzluchatel'nyj perenos jenergii v kompozicijah karbocianinovyh krasitelej v nanoob#eme micelly PAV / S.L. Efimova, A.V. Sorokin, A.N. Lebedenko, [i dr.] // Zhurn. prikl. spektr. – 2006. – T. 73. – S. 152-157./
23. Influence of dye hydrophobicity on the efficiency of fluorescence resonance energy transfer between dyes in surfactant micelles / S.L. Yefimova, A.S. Lebed, G.Ya. Guralchuk, [et al.] // Mol. Cryst. Liq. Cryst. – 2001. – V. 535. – P. 204-211.
24. Влияние гидрофобности катионных карбоцианиновых красителей DiOCn на эффективность связывания с мицеллами поверхностно-активного вещества / А.С. Лебедь, С.Л. Ефимова, Г.Я. Гуральчук, [и др.] // Журн. прикл. спектр. – 2010. – Т. 77, №2. – С. 198-203. /Vlijanie gidrofobnosti kationnyh karbocianinovyh krasitelej DiOCn na jeffektivnost' svjazyvanija s micellami poverhnostno-aktivnogo veshhestva / A.S. Lebed', S.L. Efimova, G.Ja. Gural'chuk, [i dr.] // Zhurn. prikl. spektr. – 2010. – T. 77, №2. – S. 198-203./
25. Райхард Х. Растворители в органической химии / Х. Райхард; [пер. с нем. Э.Р. Захса]. – Л.: Химия, 1973. – 152 с. /Rajhard H. Rastvoriteli v organicheskoj himii / H. Rajhard; [per. s nem. Je.R. Zahsa]. – L.: Himija, 1973. – 152 s./
26. Nano-scale liposomal container with a “signal system” for substances delivering in living cells / S.L. Yefimova, A.S. Lebed', G.Ya. Guralchuk, [et al.] // Biopolymer and Cell. - 2011. - V. 27(1). – P.47-52.
27. Comparative study of dye-loaded liposome accumulation in sensitive and resistant human breast cancer cells / S.L. Yefimova, I.Yu. Kurilchenko, T.N. Tkacheva, [et al.] // Experimental Oncology. - 2012. - V. 34(2). – P. 101-106.
28. Колычев В.Б. Спектроскопические методы в химии комплексных соединений / В.Б. Колычев, В.И. Парамонов; [под редакцией В.М. Вдовенко]. – Л.: Химия, 1964. – с. 30–73. /Kolychev V.B. Spektroskopicheskie metody v himii kompleksnyh soedinenij / V.B. Kolychev, V.I. Paramonov; [pod redakciej V.M. Vdovenko]. – L.: Himija, 1964. – s. 30–73./
29. О.В. Свердлова. Электронные спектры в органической химии. Л.: Химия, 1985. – 248 с. /O.V. Sverdlova. Jelektronnye spektry v organicheskoj himii. L.: Himija, 1985. – 248 s./
30. Bhowmik B.B. Photophysical studies of 3,3’ dioctadecyloxacarbocyanine dye in model biological membranes and different solvents / B.B. Bhowmik, S. Basu, D. Ray // Chemistry and Physics of Lipids. – 2001. – V. 109. – P. 175-183.
31. Göktürk S. Spectral studies of safranin-O in different surfactant solutions / S. Göktürk, M. Tuncay // Spectrochimica Acta Part A. – 2003. – V. 59. – P. 1857-1866.
32. Семиохин И.А. Физическая химия: Учебник / И.А. Семиохин. — Изд-во МГУ, 2001. —. 272 с. /Semiohin I.A. Fizicheskaja himija: Uchebnik / I.A. Semiohin. — Izd-vo MGU, 2001. —. 272 s./
33. Ross P.D. Thermodynamics of protein association reactions: forces contributing to stability / P.D. Ross, S.Subramanian // Biochemistry. – 1981. – V. 20. – P. 3096-3102.
34. Study of interaction of carprofen and its enantiomers with human serium albumin-I.Mechanism of binding studied by dialysis an spectroscopic methods / M.H. Rahman, T.Maruyama, T. Okada, [et al.] // Biochemical Pharmacology. – 1993. – V. 46(10). – P. 1721-1731.
Cited
How to Cite
Kurilchenko, I. Y., Yefimova, S. L., Tkacheva, T. N., Kavok, N. S., Sorokin, A. V., & Malyukin, Y. V. (1). Spectroscopic study of interactions between polymethine dyes and liposomes in aqueous solutions. Biophysical Bulletin, 1(28). Retrieved from https://periodicals.karazin.ua/biophysvisnyk/article/view/2500
Section
Molecular biophysics
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