Permeating mechanisms of erythrocyte membrane for nonelectrolytes - series of dioles
Abstract
In this study erythrocyte membrane permeability coefficients for a series of dioles have been defined by method developed. The method is based on the physico-mathematical modeling of hypotonic hemolysis process. There have been also determined membrane permeability coefficients for erythrocytes treated with (pCMBS ) which is known to block aqueous protein channels. Permeating process is shown to be conditioned both by hydrophilic-hydrophobic properties of the membrane molecules and their geometrical parameters.
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