Study of soft tissues viscoelastic properties using acoustic palpation method
Keywords:
ultrasound, radiation force, soft tissue, shear strain, relaxation, shear modulus
Abstract
The study of soft tissue shear elasticity modulus using the remotely induced shear waves is presented. Shear wave generation was carried out using transient acoustic radiation force with ultrasound intensity in the focal point equal to 145 W/cm2. The transient acoustic radiation force duration was equal to 2,18 ms. Measurements of the shear waves propagation velocity were made in the transducer focal plane by means of Doppler method using shear excitation propagation time. The following cow tissues were taken as the objects of study: liver, brain, udder, muscle tissues, spleen. The values of shear wave propagation velocity in tissues were obtained. The values of shear elasticity modulus were calculated using the known correlation between shear elasticity modulus, tissue density, and velocity. It was shown that the studied soft tissues differ in shear modulus value and, moreover, muscle tissues have high anisotropy of properties directed lengthwise and across the muscle fibers. The tissue elasticity and viscosity modulus were evaluated on basis of the sheer excitation relaxation analysis.
Downloads
Download data is not yet available.
References
1. B.S.Garra. Imaging of tissue elasticity: will it become an important clinical tool? // Proc. of the Fifth International Conference on the Ultrasonic Measurement and Imaging of Tissue Elasticity, Snowbird, Utah, USA October 8 - 11, p. 26, 2006.
2. S. Girnyk, A. Barannik, E. Barannik, V. Tovstiak, A. Marusenko, V. Volokhov. The estimation of elasticity and viscosity of soft tissues in vitro using the data of remote acoustic palpation // Ultrasound Med. Biol. - 2005. - V.32, N2. -P.211-219.
3. L. Pallwein, E. Pallwein, M. Schurich, V. Fischbach, H. Steiner, F. Frauscher. Sonoelastography of the testicles: preliminary results in the diagnosis of different pathological processes // PROCEEDINGS of the Fourth International Conference on the Ultrasonic Measurement and Imaging of Tissue Elasticity, Lake Travis. Austin, Texas, USA October 16- 19, p.31,2005.
4. N.H. Gokhale, M.S. Richards, C.R. Aroni, R.Leiderman, A.A. Oberai, P.E. Barbone. Progress in quantitative biomechanical imaging // PROCEEDINGS of the Fourth International Conference on the Ultrasonic Measurement and Imaging of Tissue Elasticity,Lake Travis. Austin, Texas, USA October 16 - 19, p.47, 2005.
5. A.F. Kolen, et al. Characterization of Cardiovascular Liver Motion for the Eventual Application of Elasticity Imaging to the Liver In Vivo // Physics in Medicine and Biology, 49: 4187-4206, 2004.
6. M. Zhang, Z.C. Wu, D.J. Rubens, K.J. Parker. Mechanical measurement of elastic properties of bovine liver and human prostate under compression // Proc. of The 4th. Int. Conf. Ultrason. Meas. Imag. Tissue Elasticity, pp. 130, 2005.].
7. M. Ugarte, A.A. Hussain, J. Marshall. An experimental study of the elastic properties of the human Bruch's mcmbrane-choroid complex: relevance to ageing//Br. J. Ophthalmol. 2006 May;90(5):621-6.
8. K.R. Nightingale, S.A. McAleavey, G.E. Trahey. Shear wave generation using acoustic radiation force: in vivo and ex vivo results // Ultrasound Med. Biol., 29(2): 1715:1723, 2003.
9. J. Bercoff. M. Tanter. M. Fink. Supersonic shear imaging: a new technique for soft tissue elasticity mapping // IEEE UFFC, 5l(4):396-409, 2004.
10. M.L. Palmeri. A.C. Sharma, R.P. Bouchard, R.W. Nightingale, K.R. Nightingale. A Finite-Element Method Model of Soft Tissue Response to Impulsive Acoustic Radiation Force // IEEE-UFFC, 52(10), 1699-1712, 2005.
11. R. Righetti, M. Righctti. J. Ophir, T.A. Krouskop. A Method For Imaging The Time-Dependent Mechanical Behavior Of Poroelastic Materials Using Axial Strain Elastography // Proc. of the Fifth International Conference on the Ultrasonic Measurement and Imaging of Tissue Elasticity, Snowbird, Utah, USA October 8 - 11, p. 91, 2006.
12. R. Righetti, J. Ophir, P. Ktonas. Axial resolution in elastography // Ultrasound Med. Biol. - 2002. - V.28, Nl. -P.101-113.
13. E.A. Barannik, S.A. Girnyk, V.V. Tovstiak. A.l. Marusenko, S.Y. Emelianov, A.P. Sarvazyan. Doppler ultrasound detection of shear waves remotely induced in tissue phantoms and tissue in vitro // Ultrasonics. - 2002. - V40, Nl-8. -P.849-852.
14. E. Barannik, S. Girnyk, V. Tovstiak, A. Barannik. A. Marusenko, V. Volokhov. Experimental study of local shear strains remotely induced by pulsed ultrasound in tissue-mimicking phantoms // Visnyk of Kharkiv National University N593. Biophysical Bulletin. - 2003. - Is. 1(12). - P.l 11-116.
15. E.A. Barannik, S.A. Girnyk, V.V. Tovstiak. A.I. Marusenko, V.A. Volohov, S.Y. Emelianov. A.P. Sarvazyan. The influence of viscosity on the shear strain remotely induced by focused ultrasound in viscoelastic media // J. Acoust. Soc. Am. - 2004. - V. 115, N5, Pt. 1. - P.2358- 2364.
16. S.F. Levinson, A. Sarvazyan, J. Yoon. J.R. Mclaughlin, O. Rudenko. Biological implications of muscle elasticity and viscosity // Proc. Of The Fifth International Conference On The Ultrasonic Measurement And Imaging Of Tissue Elasticity, Snowbird, Utah, USA October 8 - 11, P. 89, 2006.
17. B. Larrat, R. Sinkus, M. Tanter, M. Fink. High resolution magnetic resonance elastography at 7t: Applications to rheology // Proc. Of The Fifth International Conference On The Ultrasonic Measurement And Imaging Of Tissue Elasticity, Snowbird, Utah, Usa October 8 - 11, P. 65, 2006.
18. E. Barannik Acoustic Remote Palpation: The influence of tissue viscosity on the excitation and relaxation of local impulse shear strain in tissues // Proceedings of The 5Ih World Congress on Ultrasonics WCU 2003. France. Paris. -2003. - P.397-400.
19. Е. Баранник. Зависимость локальных импульсных сдвиговых возбуждений в мягких тканях от их вязко- упругих свойств // Вісник ХНУ N568. Біофіз. Вісн. - 2002. - Вип.2(11). - С.90-100.
20. Е.Баранник, С. Гирнык, А. Баранник. Восстановление вязкоупругих параметров мягких тканей по данным о возбуждении и релаксации локальных импульсных сдвиговых деформаций // Вісник Харківського національного університету N716, Біофізичний вісник, - 2005. - Вип.2(16). - С.86-91.
21. S.F. Oihman, H. Xu et al. Microscopic magnetic resonance elastography (fjMRE)// Magnetic Resonance in Medicine
- 2005. - V.54, Iss.3. - P.605-615.
22. R. Muthupillai, R.L. Ehman. Magnetic resonance tomography. // Nature Medicine. - 1996. - N2. - P.601-603.
2. S. Girnyk, A. Barannik, E. Barannik, V. Tovstiak, A. Marusenko, V. Volokhov. The estimation of elasticity and viscosity of soft tissues in vitro using the data of remote acoustic palpation // Ultrasound Med. Biol. - 2005. - V.32, N2. -P.211-219.
3. L. Pallwein, E. Pallwein, M. Schurich, V. Fischbach, H. Steiner, F. Frauscher. Sonoelastography of the testicles: preliminary results in the diagnosis of different pathological processes // PROCEEDINGS of the Fourth International Conference on the Ultrasonic Measurement and Imaging of Tissue Elasticity, Lake Travis. Austin, Texas, USA October 16- 19, p.31,2005.
4. N.H. Gokhale, M.S. Richards, C.R. Aroni, R.Leiderman, A.A. Oberai, P.E. Barbone. Progress in quantitative biomechanical imaging // PROCEEDINGS of the Fourth International Conference on the Ultrasonic Measurement and Imaging of Tissue Elasticity,Lake Travis. Austin, Texas, USA October 16 - 19, p.47, 2005.
5. A.F. Kolen, et al. Characterization of Cardiovascular Liver Motion for the Eventual Application of Elasticity Imaging to the Liver In Vivo // Physics in Medicine and Biology, 49: 4187-4206, 2004.
6. M. Zhang, Z.C. Wu, D.J. Rubens, K.J. Parker. Mechanical measurement of elastic properties of bovine liver and human prostate under compression // Proc. of The 4th. Int. Conf. Ultrason. Meas. Imag. Tissue Elasticity, pp. 130, 2005.].
7. M. Ugarte, A.A. Hussain, J. Marshall. An experimental study of the elastic properties of the human Bruch's mcmbrane-choroid complex: relevance to ageing//Br. J. Ophthalmol. 2006 May;90(5):621-6.
8. K.R. Nightingale, S.A. McAleavey, G.E. Trahey. Shear wave generation using acoustic radiation force: in vivo and ex vivo results // Ultrasound Med. Biol., 29(2): 1715:1723, 2003.
9. J. Bercoff. M. Tanter. M. Fink. Supersonic shear imaging: a new technique for soft tissue elasticity mapping // IEEE UFFC, 5l(4):396-409, 2004.
10. M.L. Palmeri. A.C. Sharma, R.P. Bouchard, R.W. Nightingale, K.R. Nightingale. A Finite-Element Method Model of Soft Tissue Response to Impulsive Acoustic Radiation Force // IEEE-UFFC, 52(10), 1699-1712, 2005.
11. R. Righetti, M. Righctti. J. Ophir, T.A. Krouskop. A Method For Imaging The Time-Dependent Mechanical Behavior Of Poroelastic Materials Using Axial Strain Elastography // Proc. of the Fifth International Conference on the Ultrasonic Measurement and Imaging of Tissue Elasticity, Snowbird, Utah, USA October 8 - 11, p. 91, 2006.
12. R. Righetti, J. Ophir, P. Ktonas. Axial resolution in elastography // Ultrasound Med. Biol. - 2002. - V.28, Nl. -P.101-113.
13. E.A. Barannik, S.A. Girnyk, V.V. Tovstiak. A.l. Marusenko, S.Y. Emelianov, A.P. Sarvazyan. Doppler ultrasound detection of shear waves remotely induced in tissue phantoms and tissue in vitro // Ultrasonics. - 2002. - V40, Nl-8. -P.849-852.
14. E. Barannik, S. Girnyk, V. Tovstiak, A. Barannik. A. Marusenko, V. Volokhov. Experimental study of local shear strains remotely induced by pulsed ultrasound in tissue-mimicking phantoms // Visnyk of Kharkiv National University N593. Biophysical Bulletin. - 2003. - Is. 1(12). - P.l 11-116.
15. E.A. Barannik, S.A. Girnyk, V.V. Tovstiak. A.I. Marusenko, V.A. Volohov, S.Y. Emelianov. A.P. Sarvazyan. The influence of viscosity on the shear strain remotely induced by focused ultrasound in viscoelastic media // J. Acoust. Soc. Am. - 2004. - V. 115, N5, Pt. 1. - P.2358- 2364.
16. S.F. Levinson, A. Sarvazyan, J. Yoon. J.R. Mclaughlin, O. Rudenko. Biological implications of muscle elasticity and viscosity // Proc. Of The Fifth International Conference On The Ultrasonic Measurement And Imaging Of Tissue Elasticity, Snowbird, Utah, USA October 8 - 11, P. 89, 2006.
17. B. Larrat, R. Sinkus, M. Tanter, M. Fink. High resolution magnetic resonance elastography at 7t: Applications to rheology // Proc. Of The Fifth International Conference On The Ultrasonic Measurement And Imaging Of Tissue Elasticity, Snowbird, Utah, Usa October 8 - 11, P. 65, 2006.
18. E. Barannik Acoustic Remote Palpation: The influence of tissue viscosity on the excitation and relaxation of local impulse shear strain in tissues // Proceedings of The 5Ih World Congress on Ultrasonics WCU 2003. France. Paris. -2003. - P.397-400.
19. Е. Баранник. Зависимость локальных импульсных сдвиговых возбуждений в мягких тканях от их вязко- упругих свойств // Вісник ХНУ N568. Біофіз. Вісн. - 2002. - Вип.2(11). - С.90-100.
20. Е.Баранник, С. Гирнык, А. Баранник. Восстановление вязкоупругих параметров мягких тканей по данным о возбуждении и релаксации локальных импульсных сдвиговых деформаций // Вісник Харківського національного університету N716, Біофізичний вісник, - 2005. - Вип.2(16). - С.86-91.
21. S.F. Oihman, H. Xu et al. Microscopic magnetic resonance elastography (fjMRE)// Magnetic Resonance in Medicine
- 2005. - V.54, Iss.3. - P.605-615.
22. R. Muthupillai, R.L. Ehman. Magnetic resonance tomography. // Nature Medicine. - 1996. - N2. - P.601-603.
Published
2007-06-05
Cited
How to Cite
Girnyk, S. A., BarannikE. А., Tovstiak, V. V., Tolstoluzhskiy, D. A., & Podzolkova, V. V. (2007). Study of soft tissues viscoelastic properties using acoustic palpation method. Biophysical Bulletin, 2(19), 98-104. Retrieved from https://periodicals.karazin.ua/biophysvisnyk/article/view/17247
Section
Medical physics
Copyright (c) 2007 Biophysical visnik
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
