The peculiarities of neuron's electrical structure are emphasised by numerical image processing
Abstract
The peculiarities of neurons' electrical structure were investigated with the computer models of CA1 pyramidal neurons of the rat hippocampus. The models are designed using the data of 3-D reconstruction of neurons' dendritic arborizations. The electrical structure of dendritic arborization was computed as the arborization of current transfer effectiveness profiles for each dendritic branch using the NEURON software. The dendrites are considered as passive cables with zero leakage at the tip ("sealed-end" boundary condition). The numerical method for emphasizing the cluster or continual character of a neuron's electrical structure was designed. The peculiarities of electrical structure for two model neurons were emphasized. They are the distinct groups of current transfer effectiveness profiles that are caused by the pattern of dendritic branching asymmetry
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References
Dendrites. Ed. Stuart G., Spruston N., Hausser M. -New York: Oxford. 1999.
Rail W. // In book: Kandel E. (ed) "Handbook of Physiology*'. V.l. American Physiological Society, Bethesda, MD. 1977. P.39-98.
Korogod S.M., Bras H., and oth. // Eur. J. Neurosci. 1994. V.6. P.1517-1527.
Korogod S.M. // Biol. Cyb. 1996. V.74. P.85-93.
Korogod S.M., Kulagina I.B. // Biol. Cyb. 1998. V.79. P.231-240.
Mainen Z.F.. Sejnowski T..I. // Nature. 1996. V 382. P.363-366.
Duijnhouwer J., Rcmme M.W.H., van Ooyen A., van Pelt J. //Neurocomputing. 2001. V.38-40. P.183-189.
Barrett J., Crill W. // J. Physiol. 1974. V.239. P.325-345.
Дюран Б., Оделл П. // Кластерный Анализ. М.: Статистика, 1977. -128с.
Pare D., Shink E., and oth. // J. Neurophysiol. 1998. V.79. P. 1450-1460.
Korogod S.M., Kulagina LB., and oth. //J. Comp. Neurol. 2000. V.422. P. 18-34.
Destexhe A., Rudolph M, Pare D. // Nat. Rev. Neurosci. 2003. V.4. P.739-751.
Cannon R.C., Wheal H.V., Turner D.A. //J. Comp. Neurol. 1999. V.413. P.619-633.
Pyapali G.K., Sik A., and oth. // J. Comp. Neurol. 1998. V.391. P.335-352.
Jack J.J.B., Noble D., Tsien R.W. // Electric Current Flow in Excitable Cells. "Clarendon". OXFORD. 1975
Koch C. // Biophysics of computation: information processing in single neurons. Computational Neuroscience, Oxford university press. New York, Oxford. 1999
Hines M.L., Carnevale N.T. // Neural Comput. 1997. V.9. P. 1179-1209.
Coleman G.B., Andrews 11.C. // Proceedings of the IEEE. 1979. V.67(5), P.773-785.
Павлидис Т. // Алгоритмы машинной графики и обработки изображений. М.: Радио и Связь, 1986, -399с.
Sholl D.A. // J. Anat. 1953. V.87. P.387-406.
Koch C, Poggio T., Torre V. // Phyl. Trans. R. Soc. Lond. B 1982. V.298. P.227-264.
Woolf T.B., Shepherd G.M., Greer C.A. // J. Neurosci. 1991. V.l(6). P.1837-1854.
Mel B.W. //Neural Computation. 1994. V.6. P.1031-1085.
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