Peculiarities of interaction calcium and copper ions with pyrimidine bases in frozen water solutions
Keywords:
nucleic acids, pyrimidine nitrogen bases, calcium and copper ions, low temperature secondary ion mass spectrometry
Abstract
Interaction of nucleic acid pyrimidine bases m13Ura, m11Thy, Cyt with calcium and copper ions in frozen water solutions was studied using low temperature fast atom bombardment mass spectrometric technique. Inspection of systems with varied concentrations of bases and chlorides of the metals have shown that base-metal associates recorded in the mass spectra are connected with finely dispersed structure of the eutectic of the frozen samples. It was revealed that the rate of the interactions and types of the associates formed are dependent on the divalent metal type. Calcium ions showed higher yields of associates with the bases in the solid frozen systems in comparison with dilute water solutions. Calcium ions produced along with electrostatically bound complexes covalent ones by substitution of a proton of a base, while copper ions produced only non-covalent low-abundant associates. In the case of thymine base which is prone to self-association, the distinctions between calcium and copper interactions were preserved on the level of the base dimers.
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References
Pushkar NS, Belous AM, editors. Aktualnye problemy kriobiologii. Kiev: Nauk. dumka; 1981. 608p. (in Russian)
Kosevich MV. Eur. Mass Spectrom. 1998;4(4):251-64.
Blagoi IuP, Sheina GG, Ivanov AIu, Radchenko ED, Kosevich MV, Shelkovskii VS, et al. Fizika nizkikh temperatur. 1999;25(10):1003-20. (in Russian)
Boryak OA, Kosevich MV, Shelkovsky VS, Blagoy YuP. Rapid Commun. In Mass Spectrom. 1996;10(2):197-9.
Boriak OA, Kosevich MV, Shelkovskii VS, Blagoi IuP. Biofizika. 1996;41(6):1207-13. (in Russian)
Kosevich MV. Biofizicheskii vestnik. 1998;2:5-14. (in Russian)
Boriak OA, Kosevich MV, Shelkovskii VS. Pribory i tekhnika eksperimenta. 1993;6;176-81. (in Russian)
Orlov VV, Kosevich MV, Boriak OA, Shelkovskii VS. Radiotekhnika i informatika. 2001;4:49-51. (in Russian)
Fogel IaM. Zhurn. tekhn. fiziki. 1976;46(3):621-4. (in Russian)
Cherepin VT. Ionnyi mikrozondovyi analiz. Kiev:Nauk. dumka;1992. 344p. (in Russian)
Skurat VE. Poluchenie i issledovanie ionov neletuchikh organicheskikh veshchestv v gazovoi faze i v vakuume. Moskva:VINITI; 1988. 176p. (in Russian)
Vaek LV, Adriaens A, Gijbels R. Mass Spectrom. Rev. 1999;18(1):1-47.
Tantcyrev GD, Nikolaev EN. Dokl. AN SSSR. 1972;206(1):151-4. (in Russian)
Ravdel AA, Ponomareva AM, editors. Kratkii spravochnik fiziko-khimicheskikh velichin. 8th edition. L:Khimiia; 1983. 232p. (in Russian)
Boryak OA, Kosevich MV, Shelkovsky VS, Blagoy YuP. Rapid Commun. In Mass Spectrom. 1995;9(11):978-84.
Boryak OA, Stepanov IO, Kosevich MV, Shelkovsky VS, Blagoy YuP. Eur. Mass Spectrom. 1996;2(6):329-39.
Kosevich MV. Fizicheskie mekhanrikhmy vtorichnoi emissii klasterov iz kondensirovanykh sred pri nizkikh temperatur [dissertation]. Kharkov; 2001. 369p. (in Russian)
Pushkar NS, Belous AM, Itkin IuA. Nizkotemperaturnaia kristallizatciia v biologicheskikh sistemakh. Kiev: Nauk. dumka; 1977. 243p. (in Russian)
Iurchenko TN, Kozlova VF. Skorniakov BA, Strona VI, Repin NV. Vliianie krioioprotektorov na biologicheskie sistemy. Kiev: Nauk. dumka; 1989. 240p. (in Russian)
Workman EJ, Reynolds SE. Phys. Rev. 1950;78(3):254-9.
Benninghoven A, Rudenauer FG, Werner HW. Secondary ion mass spectrometry: basic concepts. Instrumental aspects. Applications and trends. New York:Wiley;1987. 1226 p.
Kalinin FL, Lobov VP, Zhidkov VA. Spravochnik po biokhimii. Kiev: Nauk.dumka; 1971.1016p. (in Russian)
Verkin BI, Getmanetc VF, Mikhalchenko RS. Teplofizika nizkotemperaturnogo sublimatcionnogo okhlazhdeniia. Kiev: Nauk. dumka; 1980. 232p. (in Russian)
Tretiakov IuD, Oleinikov NN, Mozhaev AP. Osnovy kriokhimicheskoi tekhnologii. Moskva:Vyssh. shkola; 1987.143p. (in Russian)
Novikov PA, Vagner EA. Inzh.-fiz. zhurn. 1969;17(5):856-60. (in Russian)
Naberukhin IuI. Sorosovskii obrazovatelnyi zhurnal. 1996;5:41-8. (in Russian)
Tantcyrev GD, Nikolaev EN. Dokl. AN SSSR. 1972;206(1):151-4. (in Russian)
Lancaster GM, Honda F, Fukuda Y, Rabalais JW. J. Amer. Chem. Soc. 1979;101(8):1951-8.
Kosevich MV. Problemy kriobiologii. 1999;2:54-64. (in Russian)
Sunner J. Org. Mass Spectrom. 1993;28(8):805-23.
Vekey K. Mass Spectrom. Rev. 1995;14(3):195-225.
Kosevich MV, Boryak OA, Stepanov IO, Shelkovsky VS. Eur. Mass Spectrom. 1997;3(1):11-7.
Blagoi IuP, Galkin VL, Gladchenko GO, Kornilova SV, Sorokin VA, Shkorbatov AG. Metallokompleksy nukleinovykh kislot v rastvorakh. Kiev:Naukova dumka; 1991. 272p. (in Russian)
Swaminathan V, Sunddaralingam M. CRC Critical Rev. Biochem. 1979;6(3):245-336.
Kosevich MV. Eur. Mass Spectrom. 1998;4(4):251-64.
Blagoi IuP, Sheina GG, Ivanov AIu, Radchenko ED, Kosevich MV, Shelkovskii VS, et al. Fizika nizkikh temperatur. 1999;25(10):1003-20. (in Russian)
Boryak OA, Kosevich MV, Shelkovsky VS, Blagoy YuP. Rapid Commun. In Mass Spectrom. 1996;10(2):197-9.
Boriak OA, Kosevich MV, Shelkovskii VS, Blagoi IuP. Biofizika. 1996;41(6):1207-13. (in Russian)
Kosevich MV. Biofizicheskii vestnik. 1998;2:5-14. (in Russian)
Boriak OA, Kosevich MV, Shelkovskii VS. Pribory i tekhnika eksperimenta. 1993;6;176-81. (in Russian)
Orlov VV, Kosevich MV, Boriak OA, Shelkovskii VS. Radiotekhnika i informatika. 2001;4:49-51. (in Russian)
Fogel IaM. Zhurn. tekhn. fiziki. 1976;46(3):621-4. (in Russian)
Cherepin VT. Ionnyi mikrozondovyi analiz. Kiev:Nauk. dumka;1992. 344p. (in Russian)
Skurat VE. Poluchenie i issledovanie ionov neletuchikh organicheskikh veshchestv v gazovoi faze i v vakuume. Moskva:VINITI; 1988. 176p. (in Russian)
Vaek LV, Adriaens A, Gijbels R. Mass Spectrom. Rev. 1999;18(1):1-47.
Tantcyrev GD, Nikolaev EN. Dokl. AN SSSR. 1972;206(1):151-4. (in Russian)
Ravdel AA, Ponomareva AM, editors. Kratkii spravochnik fiziko-khimicheskikh velichin. 8th edition. L:Khimiia; 1983. 232p. (in Russian)
Boryak OA, Kosevich MV, Shelkovsky VS, Blagoy YuP. Rapid Commun. In Mass Spectrom. 1995;9(11):978-84.
Boryak OA, Stepanov IO, Kosevich MV, Shelkovsky VS, Blagoy YuP. Eur. Mass Spectrom. 1996;2(6):329-39.
Kosevich MV. Fizicheskie mekhanrikhmy vtorichnoi emissii klasterov iz kondensirovanykh sred pri nizkikh temperatur [dissertation]. Kharkov; 2001. 369p. (in Russian)
Pushkar NS, Belous AM, Itkin IuA. Nizkotemperaturnaia kristallizatciia v biologicheskikh sistemakh. Kiev: Nauk. dumka; 1977. 243p. (in Russian)
Iurchenko TN, Kozlova VF. Skorniakov BA, Strona VI, Repin NV. Vliianie krioioprotektorov na biologicheskie sistemy. Kiev: Nauk. dumka; 1989. 240p. (in Russian)
Workman EJ, Reynolds SE. Phys. Rev. 1950;78(3):254-9.
Benninghoven A, Rudenauer FG, Werner HW. Secondary ion mass spectrometry: basic concepts. Instrumental aspects. Applications and trends. New York:Wiley;1987. 1226 p.
Kalinin FL, Lobov VP, Zhidkov VA. Spravochnik po biokhimii. Kiev: Nauk.dumka; 1971.1016p. (in Russian)
Verkin BI, Getmanetc VF, Mikhalchenko RS. Teplofizika nizkotemperaturnogo sublimatcionnogo okhlazhdeniia. Kiev: Nauk. dumka; 1980. 232p. (in Russian)
Tretiakov IuD, Oleinikov NN, Mozhaev AP. Osnovy kriokhimicheskoi tekhnologii. Moskva:Vyssh. shkola; 1987.143p. (in Russian)
Novikov PA, Vagner EA. Inzh.-fiz. zhurn. 1969;17(5):856-60. (in Russian)
Naberukhin IuI. Sorosovskii obrazovatelnyi zhurnal. 1996;5:41-8. (in Russian)
Tantcyrev GD, Nikolaev EN. Dokl. AN SSSR. 1972;206(1):151-4. (in Russian)
Lancaster GM, Honda F, Fukuda Y, Rabalais JW. J. Amer. Chem. Soc. 1979;101(8):1951-8.
Kosevich MV. Problemy kriobiologii. 1999;2:54-64. (in Russian)
Sunner J. Org. Mass Spectrom. 1993;28(8):805-23.
Vekey K. Mass Spectrom. Rev. 1995;14(3):195-225.
Kosevich MV, Boryak OA, Stepanov IO, Shelkovsky VS. Eur. Mass Spectrom. 1997;3(1):11-7.
Blagoi IuP, Galkin VL, Gladchenko GO, Kornilova SV, Sorokin VA, Shkorbatov AG. Metallokompleksy nukleinovykh kislot v rastvorakh. Kiev:Naukova dumka; 1991. 272p. (in Russian)
Swaminathan V, Sunddaralingam M. CRC Critical Rev. Biochem. 1979;6(3):245-336.
Published
2018-06-25
Cited
How to Cite
Kosevich, M. V., Boryak, O. A., Shelkovsky, V. S., Orlov, V. V., Chagovets, V. V., Karachevtsev, V. A., & Blagoi, Y. P. (2018). Peculiarities of interaction calcium and copper ions with pyrimidine bases in frozen water solutions. Biophysical Bulletin, 1(12), 24-28. Retrieved from https://periodicals.karazin.ua/biophysvisnyk/article/view/12228
Section
Molecular biophysics
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