Associations of indicators of the physical component of health with clinical-neuroimaging data of patients who have suffered ischemic stroke in the vertebrobasilar basin
Abstract
Summary. A stroke significantly worsens the quality of life of patients. An expert report from the Polish National Program for the Prevention and Treatment of Cerebral Stroke in 2001 recommends assessing quality of life during post-stroke rehabilitation. The authors report on parameters that may influence quality of life, in particular, age, gender, and functional status, including degree of disability, cognitive impairment, depression, and social status.
The purpose of the study is to evaluate the indicators of the physical component of quality of life in patients with different types of ischemic stroke, depending on the follow-up, the size of the ischemic lesion, and the severity of the stroke.
Materials and methods. The study included 105 people diagnosed with ischemic stroke in the vertebrobasilar basin. Study groups were formed depending on the follow-up, the type of ischemic stroke, the size of the ischemic lesion, and the severity of the stroke. The SF-36 general questionnaire was used to assess quality of life.
Results. In patients with ischemic stroke, the physical component of health did not depend on catamnesis, but it was probably lower in cardioembolic type of stroke (according to indicators of physical functioning, role functioning and general state of health), in patients with a lesion size >100 cm3 (according to indicators of physical functioning and general state of health), as well as with a severe degree of severity of ischemic stroke at the time of admission (according to indicators of physical functioning, role functioning).
In patients with ischemic stroke, a probable inverse weak strength of association was established between the size of the lesion and physical functioning (r=-0.25; p<0.05), role functioning (r=-0.19; p<0.05) and general health (r=-0.29; p<0.05), as well as between stroke severity on the NIHSS scale and physical functioning (r=-0.34; p<0.05).
Conclusions. The quality of life of patients with ischemic stroke, in particular the physical component of health, is related to the severity of the stroke at admission and the size of the lesion.
Downloads
References
2. Vos T., Allen C., Arora M. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the global burden of disease study 2015. Lancet. 2016. № 388(10053). Р. 1545–1549.
3. Jarosławski S., Jarosławska B., Błaszczyk B., Auqier P., Toumi, M. Health-related quality of life of patients after ischaemic stroke treated in a provincial hospital in Poland. Journal of market access & health policy. 2020. № 8(1). Р. 1775933. https://doi.org/10.1080/20016689.2020.1775933
4. Qureshi A. I., Ziai W. C., Yahia A. M., et al. Stroke-free survival and its determinants in patients with symptomatic vertebrobasilar stenosis: a multicenter study. Neurosurgery. 2003. № 52. Р. 1033–1039, discussion 1039–1040.
5. Abuzinadah A. R., Alanazy M. H., Almekhlafi M. A., et al. Stroke recurrence rates among patients with symptomatic intracranial vertebrobasilar stenoses: systematic review and meta-analysis. J Neurointerv Surgery. Published online ahead of print 2014. December 11. http://jnis.bmj.com/content/early/2014/12/11/neurintsurg-2014–011458.long. Accessed April 27, 2021.
6. Yu J., Zhang S., Li M. L., et al. Relationship between the geometry patterns of vertebrobasilar artery and atherosclerosis. Neurol. 2018 Jun 12. № 18(1). Р. 83.
7. Caplan L., Chung C. S., Wityk R., et al. New England medical center posterior circulation stroke registry: I. Methods, data base, distribution of brain lesions, stroke mechanisms, and outcomes. J Clin Neurol. 2005. № 1. Р. 14–30. doi: 10.3988/jcn.2005.1.1.14.
8. McKevitt C., Redfern J., La-Placa V., et al. Defining and using quality of life: a survey of health care professionals. Clin Rehabil. 2003. № 17(8). Р. 865–870.
9. Haley W. E., Roth D. L., Kissela B., et al. Quality of life after stroke: a prospective longitudinal study. Qual Life Res. 2011. № 20(6). Р. 799–806.
10. Szczudlik A., Kozubski W., Drozdowski W., et al. Postępowanie w ostrym udarze niedokrwiennym mózgu. Raport zespołu ekspertów Narodowego Programu Profilaktyki i Leczenia Udaru Mózgu. Przewodnik Lekarza/Guide for GPs. 2003. № 4. Р. 65–82.
11. Xie J., Wu E. Q., Zheng Z. J., et al. Impact of stroke on health-related quality of life in the noninstitutionalized population in the USA. Stroke. 2006. № 37(10). Р. 2567–2572.
12. Jaracz K., Kozubski W. Quality of life in stroke patients. Acta Neurol Scand. 2003. № 107(5). Р. 324–329.
13. Opara J. A., Jaracz K. Quality of life of post-stroke patients and their caregivers. J Med Life. 2010. № 3(3). Р. 216–220.
14. Jaracz K, Kozubski W. Quality of life after stroke. Part I – a prospective study. Udar Mózgu Problemy Interdyscyplinarne. 2001. № 3. Р. 55–62.
15. Schindel D., Schneider A., Grittner U., et al. Quality of life after stroke rehabilitation discharge: a 12-month longitudinal study. Disabil Rehabil. 2019. № 1-10. DOI: 10.1080/09638288.2019.1699173
16. Rotter I. Effect of functional capacity, coexisting depression and some socio-demographic factors on the quality of life in patients with ischemic cerebrovascular stroke. Ann Acad Med Stetin. 2002. № 48. Р. 301–316.
17. Verstraeten S. M. M., Mark R. E., Sitskoorn M. M. Motor and cognitive impairment after stroke. Stroke Res Ther. 2016. № 1.
18. Cumming T. B., Brodtmann A., Darby D., et al. The importance of cognition to quality of life after stroke.J Psychosom Res. 2014. № 77(5). Р. 374–379.
19. Stelmach A., Lorencowicz R., Jasik J., et al. Factors determining the assessment of quality of life made by patients who have had a stroke. J Neurol Neurosur Nurs. 2016. № 5(4). Р. 136–143.
20. Hage V. The NIH stroke scale: a window into neurological status. Nursing Spectrum. 2011. № 24(15).Р. 44–49.
21. Ware J. E., Sherbourne C. D. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Medical Care. 1992. № 30. Р. 473–483.
22. Фещенко Ю. І., Мостовой Ю. М., Бабійчук Ю. В. Процедура адаптації міжнародного опитувальника оцінки якості життя в Україні. Досвід застосування у хворих на бронхіальну астму. Укр. пульмонол. журн. 2002. № 3. Р. 9–11.
23. Mishra G. D., Hockey R., Dobson A. J. A comparison of SF-36 summary measures of physical and mental health for women across the life course. Qual Life Res. 2014. № 23(5). Р. 1515–1521.
24. Gray L. J., Sprigg N., Bath P. M., et al. Sex differences in quality of life in stroke survivors: data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST). Stroke. 2007. № 38(11). Р. 2960–2964. [PubMed] [Google Scholar]
25. Pickard A. S., Johnson J. A., Feeny D. H, et al. Agreement between patient and proxy assessments of health-related quality of life after stroke using the EQ-5D and health utilities index. Stroke. 2004. № 35(2). Р. 607–612.
26. Muller-Nordhorn J., Nolte C. H., Rossnagel K., et al. The use of the 12-item short-form health status instrument in a longitudinal study of patients with stroke and transient ischaemic attack. Neuroepidemiology. 2005. № 24(4). Р. 196–202.
27. Kapoor A., Si K., Yu A., et al. Younger age and depressive symptoms predict high risk of generalized anxiety after stroke and transient ischemic attack. Stroke. 2019. № 50(9). Р. 2359–2363.
28. Westerlind E., Persson H. C., Eriksson M., et al. Return to work after stroke: a Swedish nationwide registry-based study. Acta Neurol Scand. 2020. № 141(1). Р. 56–64.
29. Varona J. F., Bermejo F., Guerra J. M., Molina J. A. Long-term prognosis of ischemic stroke in young adults. Study of 272 cases. J Neurol. 2004. № 251(12). Р. 1507–1514.
30. Yoon S., Kim H. Y., Kim S. R. A prediction model of health-related quality of life in young adult patients with stroke. J Clin Nurs. 2021. № 30(13-14). Р. 2023–35. https://doi.org/10.1111/jocn.15755.
31. Kono Y., Terasawa Y., Sakai K., et al. Risk factors, etiology, and outcome of ischemic stroke in young adults: a Japanese multicenter prospective study. J Neurol Sci. 2020. № 417. Р. 117068.
32. Yeoh Y. S., Koh G. C., Tan C. S., et al. Can acute clinical outcomes predict health-related quality of life after stroke: a one-year prospective study of stroke survivors. Health Qual Life Outcomes. 2018. № 16(1). Р. 221.
This work is licensed under a Creative Commons Attribution 4.0 International License.