Lasers in research and therapy: discoveries throughout the years
Abstract
In low-level laser therapy research there has been a clear division of physicists studying the laser itself and some specific cellular function in vitro, photobiologists studying cellular and molecular effects or medical doctors studying clinical effects. Effects of laser light have been under dispute ranging from ineffective to dangerous, cytotoxic, mutagenic, carcinogenic and proliferative effects. For years medical field based their reserve on lack of studies, poor studies, lack of evidence or no results. This has largely been due to the fact that quite a number of studies had been carried out in clinics with minimal funding, rendering double blind studies near impossible.
With the development of better and cheaper equipment cellular effects of laser and light became a popular topic of research. Clinical results gave encouraging reasons for further studies at the cellular and molecular level. This paper attempts to give a chronological review of notable studies in the use of low level lasers and light in the treatment of numerous medical conditions, focusing on the developing use of low level laser in the treatment of neurological diseases.
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