He-Ne laser irradiation encourages reparative processes after cartilage loss and enhances the growth of autologous cartilage grafts
Abstract
The external auricle has a high potential for injury due to its exposed and unprotected position alongside the head. Several of authors have demonstrated the enhancing role of laser radiation of blue and red regions on the early regenerative processes. Many changes occur on the sub cellular levels for example acceleration of collagen and its precursors. This is very important for the healing process especially when known that the collagen form about 50% of the dry weight of the intercellular matrix.
The main purpose of this project was to determine the ability of filling a defect resulting in massive cartilage loss with newly formed tissue which is cartilaginous in origin with just little fibrous tissue . This process depends upon preservation of blood supply to the cartilage which formed the boundaries of the hole left after removing the specimens. The cartilage of the ear has no other blood supply except that supplied by the overlying skin.
Rabbit ears with experimental damage were irradiated with He–Ne laser (632,8 nm wavelength, 5mW power) applied directly after the operation and daily for 7 days after that with 10 minutes / session, by direct contact of the beam source on the line of the incision.
Results showed that low lever laser irradiation enhances microcirculation and seemed to be unique in normalization of the functional features of the area which irradiated with it in addition to rapid increase in the level of Adenosine, Growth hormone, GH and Fibroblast growth factor, FGF. Fiber/capillary, F/C ratio and Capillary’s diameter proliferated the aria with marked increase in the diameter of the original blood vessels. Thus the first important factor encourage the healing was provided by the irradiation with the He-Ne laser.
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References
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