A comparative experimental-morphological study of the methods of chemodestruction, cryodestruction and laser destruction of the peripheral nerve trunk
Abstract
An experimental morphological study of the methods of chemodestruction, cryodestruction and laser destruction as those of medical denervation in pharmacoresistant forms of prosopalgia was carried out. The obtained data testify to the presence of evident destructive macro- and microscopic changes both in the nerve trunk and its surrounding tissues when using alcoholic chemodestruction. A lesser degree of morphological changes was observed in phenol chemodestruction. Cryodestruction was characterized by morphological signs of persistent denervation with a minimal manifestation of perifocal changes in the surrounding tissues. The laser method of denervation resulted in replacement of destruction by regeneration in the early period. Perifocal changes were minimal.
Downloads
References
Karlova VA, editor. Neurology of the face. Moscow: Me- dicina Publ; 1991. 288 p. (in Russian)
Tsimbalyuk VІ, Dmіterko IP, Sapon MA, et al. Ethiolo- gy, pathogenesis and neurochralgia licone neuralgia of the tripartite nerve (looking at the tutorial). Ukrainskij nejrohіrurgіchnij zhurnal [Ukrainian neurosurgical jour- nal]. 2001;4:40-6. (in Ukrainian)
Sapon NA. Questions of the pathogenesis of trigemi- nal neuralgia (postulates, contradictions and new ap- proaches). First post. Ukrainskij nejrohіrurgіchnij zhur- nal [Ukrainian neurosurgical journal]. 2005;2:54-9. (in Ukrainian)
Sapon NA. Questions of the pathogenesis of trigeminal neuralgia (postulates, contradictions and new approaches). The second message. Ukr. nejrohіrurg. zhurnal [Ukr. neurosurg. journal]. 2005;4:72-6. (in Ukrainian)
Schloesser C. Zur Behandlung der Neuralgien durchAl- kohol einspritzungen. Berl. Klin. Wschr. 1906, S. 82.
Kirschner M. Die Punktionstechnik und die Elektroko- agulation des Ganglion Gasseri. Uber “gezielte” Opera- tionen. Arch. Klin. Chir. 1933; Bd.176: 581-620.
Jefferson A. Trigeminal neuralgia. J. Neurol. Neurosurg. Psychiatry. 1963; 26: 345-52.
Vasin NYa. On the method and results of the phenol blockade of the Gasser node with severe forms of facial pain. Zhurnal Voprosy nejrohirurgii im. N.N. Burdenko [Journal Questions neurosurgery named after N.N. Bur- denko]. 1973;2:16-22. (in Russian)
Livshic LYa. Nevralgiya trojnichnogo nerva i ee lechenie metodom napravlennoj gidrotermicheskoj destrukcii chuvstvitel'nogo trigeminal'nogo koreshka [Neuralgia of the trigeminal nerve and its treatment by the method of directed hydrothermal destruction of the sensitive trigem- inal root] [dissertation]. Saratov; 1968. 38 p. (in Russian)
Posokhov MF, Chernenkov VG, Pihtіn OV, inventors; SI “Institute of Neurology, Psychiatry and Narcology of NAMS of Ukraine”, assignee. Sposіb lіkuvannya nevral- gіi trіjchastogo nervu [Method of treatment neuralgia of the trigeminal nerve]. Patent 69236 Ukraine, МПК A61B 18/02 No. u201111451; September 28, 2011; 04/25/2012, bul. № 8/2012. (in Ukrainian)
Tsymbalyuk VI, Posohov NF, Sapon NA, et al. Cryode- struction of the sensitive root in the treatment of severe forms of trigeminal neuralgia. Byulleten' Ukrainskoj Associacii Nejrohirurgov [Bulletin of the Ukrainian As- sociation of Neurosurgeons]. 1997;3:14-6. (in Russian)
Prodan AI, Bengus LM, Sirenko AA. The morphology of the sciatic nerve after local cryotherapy. Ortopediya, travmatologiya i protezirovanie [Orthopedics, trauma- tology and prosthetics]. 2010;2:66-72. (in Russian)
Cosman ER, Nashold BS, Overmann-Levit J. Theo- retical aspects of the radio entry zone. Neurosurgery. 1984;15:945-50.
Posohov MF, Tsymbalyuk VІ, Pihtіn OV, Posohov SM, Gorbunov OV, Korobov AM, Holіn VV, inventors; SI “Institute of Neurology, Psychiatry and Narcology of the NAMS of Ukraine”, assignee. Sposіb lіkuvannya nevralgіi trіjchastogo nervu metodom lazernoi nejrotomіi per- iferichnih gіlok [Method of treatment neuralgia of the trigeminal nerve by the method of laser neurotomy of peripheral branches. Patent 76598 Ukraine, МПК A61N 5/06. No. u201207521; 06/19/2012; 01/10/2013 bulle- tin No. 1/2013. (in Ukrainian)
Posohov NF, Tsymbalyuk VI, Gorbunov OV, et al. Ex- perimental and morphological study of the methods of alcohol, cryo and laser destruction of the nerve trunk. . Materialy XXXIX Mezhdunarodnoj nauchno-praktich- eskoj konferencii. Primenenie lazerov v medicine i bi- ologii [Proceedings of the XXXIX International Scientific and Practical Conference. The use of lasers in medicine and biology]; 2013 May 22-24; Kharkov. Kharkov; 2013; p. 126-7. (in Russian)
Kozel AI. New minimally invasive laser technologies in the practice of the Chelyabinsk State Institute of Laser Surgery. Izvestiya Chelyabinskogo nauchnogo centra [Proceedings of the Chelyabinsk Scientific Center]. 2001;2(11):112-6. (in Russian)
Ismagilova ST. Dinamika morfologicheskih izmenenij trojnichnogo nerva pri destrukcii ego chuvstvitel'nogo koreshka vysokointensivnym lazernym izlucheniem (ehksperimental'noe issledovanie) [The dynamics of the morphological changes of the trigeminal nerve during the destruction of its sensitive root by high-intensity laser ra- diation (experimental study)] [dissertation]. Chelyabinsk; 1997. 22 p. (in Russian)
Burchiel K, editor. Wilkins RH. Trigeminal neuralgia: his- tory, with emphasis on surgical treatment. Surgical Man- agement of Pain. New York: Thieme; 2002. p. 288-303.
Han KR, Chae YJ, Lee JD, et al. Trigeminal neuralgia: long-term clinical eff eness on pain. International Journal of Medical Sciences. 2017;14(1):29-36.
Shengelia NS. Kliniko-ehksperimental'noe obosnovanie metoda alkogolizacii pri nevralgii trojnichnogo nerva (Kliniko-morfologicheskoe issledovanie) [Clinical and ex- perimental substantiation of the method of alcoholism in trigeminal neuralgia (Clinical and morphological study)]. Tbilisi: Mecniereba Publ; 1981. 132 p. (in Russian)
Megdyatov RS. Nevralgiya trojnichnogo nerva [Neuralgia of the trigeminal nerve]. Moscow: Medicina Publ; 1999. 144 p. (in Russian)
Savickaya ON, Dzugaeva SB. About neuralgia (neuritis) of the trigeminal nerve. Zhurnal nevropatologii i psihiatrii im. S.S. Korsakova [SS Korsakov Journal of Neuropathol- ogy and Psychiatry]. 1971;5:690-4. (in Russian)
Wood KM. The use of phenol as a neurolytic agent. A review. Pain 1978;5:205-29.
Hernández-Santos JR, Plancarte R, Oliva S, et al. Bloqueo de ganglio de gasser con glicerol versus fenol intragas- seriano para neuralgia trigeminal. Rev. Soc. Esp. Dolor. 1999;6:269-76.
Laks A, Nurmiste A. The introduction of glycerol into the trigeminal cistern in the treatment of the trigeminal nerve. Aktual'nye voprosy nevrologii i nejrohirurgii. Ma- terialy III siezda nevrologov i nejrohirurgov Ehstonskoj SSR [Topical issues of neurology and neurosurgery. Ma- terials of the III congress of neurologists and neurosur- geons of the Estonian SSR]. 1989;T.1:104-6. (in Russian)
Livshits A. Directional hydrothermal destruction of the sensitive root of the trigeminal nerve as a method for treating trigeminal neuralgia. Voprosy nejrohirurgii [Neurosurgery issues]. 1965;4:47-52. (in Russian)
Berezhnoj BI. Experience with hydrothermal destruction of sensitive roots of the Gasser's node in trigeminal neu- ralgia. Materialy 1 konferencii nejrohirurgov Respubliki Krym [Proceedings of the 1st conference of neurosur- geons of the Republic of Crimea]; Kerch; 1995. p. 61-63. (in Russian)
Meglio M, Cioni B. Percutaneous procedures for tri- geminal neuralgia: Microcompression versus radiofre- quency thermocoagulation. Personal experience. Pain. 1989;38(1):9-16.
Prodan OІ, Bengus LM, Sirenko OA, et al. Morphological images of the fusion nerve using your ears for electrical coagulation (experimental further). Naukovij vіsnik Uzhgorods'kogo Un-tu [Science Bulletin of Uzhhorod Uni]. 2007;32:149-52. (in Ukrainian)
Bengus LM, Prodan AI, Sirenko AA. Characteristics of the morphological changes of the sciatic nerve during its damage by electrocoagulation and cryotherapy. Problemi osteologіi [Problems of Osteology]. 2008;10(1-2): 59-62. (in Russian)
TroyanVV, Glebov MA. Comparative results of surgical methods for treating trigeminal neuralgia. Nejrohirurgiya [Neurosurgery]. 2007;1:25-8. (in Russian)
Mogila VV, Litvinenko SV. The current state of the problem of treating trigeminal neuralgia. Nejrohirurgiya [Neurosurgery]. 2002;4:12-4. (in Russian)
Sipityj VI, Posohov NF, Pyatikop VA. Kriohirurgicheskoe lechenie tyazhelyh form nevralgii trojnichnogo nerva [Cryosurgical treatment of severe forms of trigeminal neu- ralgia]. Kharkov: Osnova Publ; 1995. 112 p. (in Russian)
Murinec-Markevich BN, Sipityj VI, Krasnikov AR, et al. Neurosurgical cryoprobe for treating trigeminal neuralgia Preprint Fiziko-tekhnicheskogo instituta nizkih tempera- tur Akademii nauk USSR [Preprint of the Physico-Tech- nical Institute of Low Temperatures of the Academy of Sciences of the Ukrainian SSR]. Kharkov; 1986; 35. 7 p. (in Russian)
Ismagilova ST, Kozel' A.I. Surgical treatment of tri- geminal neuralgia with high-intensity laser radiation. Materialy II siezda nejrohirurgov Rossijskoj Federacii [Proceedings of the II Congress of Neurosurgeons of the Russian Federation]; 1998 June 16-19; Nizhny Novgorod. St. Petersburg; 1998. p. 203. (in Russian)
Matkіvskij RM. Ultrastructure organ of the synergic nerve. Klіnіchna anatomіya ta operativna hіrurgіya [Clin- ical anatomy and operative surgery]. 2007;6(1):16-9. (in Ukrainian)
Hem A, Kormak D. Gistologiya [Histology]. Moscow: Mir Publ, 1983. V. 3; 293 p. (in Russian)
Cherepnev GV, Chelyshev YuA. . Molecular and cel- lular aspects of pharmacological stimulation of nerve regeneration. Eksperimentalnaya i klinicheskaya far- makologiya [Experimental and clinical pharmacology]. 2001;64(3):67-71. (in Russian)
Schudlo NA. Analysis of myeloarchitectonics of regener- ating peripheral nerve of experimental animals in remote periods after microsurgical suture and electrosmulation. Annaly hirurgii [Annals of Surgery]. 2006;3:58-61. (in Russian)
Turgut M, Uyanikgil Y, Baka M. et al. 40. Pinealectomy exaggerates and melatonin treatment suppresses neu- roma formation of transected sciatic nerve in rats: gross morphological, histological and stereological analysis. J. Pineal. Res. 2005;38(4):R.284-91.
Bagrіj MM, Dіbrova VA., editors. Metodiki morfologіch- nih doslіdzhen: monografіya [Methods of morphological research: monograph]. Vinnitsa: Nova Kniga Publ, 2016. 328 p. (in Ukrainian)
