Monte Carlo Code for Calculating the Elastic and Inelastic Scattering Cross Section Along with Mean Free Path of Positron Scattering in Kidney, Lung and Thyroid Organs
Abstract
This research calculated the total cross sections for positron scattering in kidney, lung, and thyroid tissues along an energy range of 100 eV to 1 MeV. Monte Carlo methods were employed to determine both elastic and inelastic integral cross sections, utilizing the Rutherford formula for elastic scattering and the Gryzinski excitation function for inelastic processes. A comparison was made between elastic and Penelope elastic cross sections. The study also examined elastic, inelastic, and total mean free paths as functions of positron energy for all three tissue types. The computational approach is designed to be broadly applicable across different materials. We observed significant differences in cross-section profiles and in the energy dependencies of the mean free path between tissues, attributing these variations to distinct inelastic-scattering characteristics inherent to each material. While the systematic uncertainties in the computational algorithm are challenging to quantify precisely, we believe they are largely systematic.
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References
M. Danch-Wierzchowska, D. Borys, B. Bobek-Bilewicz, M. Jarzab, and A. Swierniak, “Simplification of breast deformation modelling to support breast cancer treatment planning,” Biocybern. Biomed. Eng. 36(4), 531–536 (2016). https://doi.org/10.1016/j.bbe.2016.06.001
I. Adesida, R. Shimizu, and T. E. Everhart, “A study of electron penetration in solids using a direct Monte Carlo approach,” J. Appl. Phys. 51(11), 5962–5969 (1980). https://doi.org/10.1063/1.327515
Y.A. Üncü, G. Sevim, O. Ağar, and H. Özdoğan, “Mass attenuation coefficient, stopping power, and penetrating distance calculations via Monte Carlo simulations for cell membranes,” Kuwait J. Sci. 50(1A), 1–12 (2023). https://doi.org/10.48129/kjs.15657
O.N. Vassiliev, Monte Carlo Methods for Radiation Transport, (Springer International Publishing, Cham, 2017). https://doi.org/10.1007/978-3-319-44141-2
I. Low, and Z. Yin, “Entanglement Entropy is Elastic Cross Section,” J. Med. Phys. 49, 155–166 (2024). http://arxiv.org/abs/2410.22414
K. Koç, and A. Çetin, “Investigation of Interactions Between Low Energy Positrons and DNA Using the Monte-Carlo method,” NeuroQuantology, 13(2), 160–169 (2015). https://doi.org/10.14704/nq.2015.13.2.852
C.E. Chika, “Estimation of Proton Stopping Power Ratio and Mean Excitation Energy Using Electron Density and Its Applications via Machine Learning Approach,” J. Med. Phys. 49(2), 155–166 (2024). https://doi.org/10.4103/jmp.jmp_157_23
C. Hugenschmidt, “Positrons in surface physics,” Surf. Sci. Rep. 71(4), 547–594 (2016). https://doi.org/10.1016/J.SURFREP.2016.09.002
J.C. Ashley, “Interaction of Low-Energy Electrons with Condensed Matter: Stopping Powers and Inelastic Mean Free Paths from Optical Data,” J. Electron. Spectros. Relat. Phenomena, 46, 199–214 (1988).
Z. Tan, et al., “Cross sections of electron inelastic interactions in DNA,” Radiat. Environ. Biophys. 43(3), 173–182 (2004). https://doi.org/10.1007/s00411-004-0249-4
Z. Tan, et al., “Electron stopping power and mean free path in organic compounds over the energy range of 20-10,000 eV,” Nucl. Instrum. Methods Phys. Res. B, 222(1-2), 27–43 (2004). https://doi.org/10.1016/j.nimb.2004.02.017
L.H. Cai, B. Yang, C.C. Ling, C.D. Beling, and S. Fung, “Monte carlo simulation of positron induced secondary electrons in thin carbon foils,” Journal of Physics: Conference Series, Institute of Physics Publishing, 262, 012009 (2011). https://doi.org/10.1088/1742-6596/262/1/012009
K. Ratnavelu, M. J. Brunger, and S.J. Buckman, “Recommended Positron Scattering Cross Sections for Atomic Systems,” J. Phys. Chem. Ref. Data, 48(2), (2019). https://doi.org/10.1063/1.5089638
B.P. Nigam, M.K. Sundaresan, and T.-Y. Wu, “Theory of Multiple Scattering: Second Born Approximation and Corrections to Molière’s Work,” Physical Review, 115(3), 491–502 (1959). https://doi.org/10.1103/PhysRev.115.491
S. Yalcin, U. Akar Tarim, O. Gurler, O. Gundogdu, and D. A. Bradley, “Screening parameter for elastic scattering of electrons,” Radiation Effects and Defects in Solids, 176(9–10), 919–939 (2021). https://doi.org/10.1080/10420150.2021.1975709
M. Gryzinski, “Two-Particle Collisions. II. Coulomb Collisions in the Laboratory System of Coordinates,” Physical Review, 138(2), 322–335 (1965).
M. V. Manjunatha, and T. K. Umesh, “Effective atomic number of some rare earth compounds determined by the study of external bremsstrahlung,” J. Radiat. Res. Appl. Sci. 8(3), 428–432 (2015). https://doi.org/10.1016/j.jrras.2015.03.005
V. De Smet, R. Labarbe, F. Vander Stappen, B. Macq, and E. Sterpin, “Reassessment of stopping power ratio uncertainties caused by mean excitation energies using a water-based formalism,” Med. Phys. 45(7), 3361–3370 (2018). https://doi.org/10.1002/mp.12949
G.S. Ibbott, “Radiation Dosimetry: Electron Beams with Energies Between 1 and 50 MeV (ICRU Report No. 35),” Med. Phys. 12(6), 813–813 (1985). https://doi.org/10.1118/1.595780
M. Grvzinski, “Two-Particle Collisions. I. General Relations for Collisions in the Laboratory System,” Physical Review, 138(2), 305–321 (1965).
M. Asai, M.A. Cortés-Giraldo, V. Giménez-Alventosa, V. Giménez Gómez, and F. Salvat, “The PENELOPE Physics Models and Transport Mechanics. Implementation into Geant4,” Front. Phys. 9, 1–20 (2021). https://doi.org/10.3389/fphy.2021.738735
N.J. Carron, An Introduction to the Passage of Energetic Particles through Matter, (Taylor & Francis Group, California, USA, 2021). https://doi.org/10.1201/9781420012378
M. Dapor, “Comparison of Electron Compton Scattering with Positron Compton Scattering in Polyethylene,” Materials, 18(7), 1–10 (2025). https://doi.org/10.3390/ma18071609
A. Alshibel, and K. T. Osman, “Mass Stopping Power and Range of Alpha Particles in Biological Human Body Tissues (Blood, Brain, Adipose and Bone),” OAlib, 10(10), 1–17 (2023). https://doi.org/10.4236/oalib.1110775
A.B. Denison, and H. H. Farrell, “Positron mean free paths between 50 eV and 40 keV,” Phys. Rev. B: Condens. Matter. Mater. Phys. 69(10), 1–8 (2004). https://doi.org/10.1103/PhysRevB.69.104302
S.V. Stepanov, V.M. Byakov, and P.S. Stepanov, “Positronium in Biosystems and Medicine: A New Approach to Tumor Diagnostics Based on Correlation between Oxygenation of Tissues and Lifetime of the Positronium Atom,” Physics of Wave Phenomena, 29(2), 174–179 (2021). https://doi.org/10.3103/S1541308X21020138
E.C. Emond, A.M. Groves, B.F. Hutton, and K. Thielemans, “Effect of positron range on PET quantification in diseased and normal lungs,” Phys. Med. Biol. 64(20), 1–16 (2019). https://doi.org/10.1088/1361-6560/ab469d
H.I. Coerts, B. de Keizer, and F.A. Verburg, “Advances in the Development of Positron Emission Tomography Tracers for Improved Detection of Differentiated Thyroid Cancer,” Cancers (Basel), 16(7), 1–12 (2024). https://doi.org/10.3390/cancers16071401
ICRU, “Tissue substitutes in radiation dosimetry ana measurement ICRU report 44,” Bethesda, (1989).
M. Kefalati, S.F. Masoudi, and A. Abbasi, “Effect of human body position on gamma radiation dose rate from granite stones,” J. Environ. Health. Sci. Eng. 19(1), 933–939 (2021). https://doi.org/10.1007/s40201-021-00660-7
A. Arectout, et al., “Investigation of photon interaction parameters in Human Body Tissues using GAMOS, FLUKA, and XCOM Studies,” Nuclear Analysis, 4(1), 1–11 (2025). https://doi.org/10.1016/j.nucana.2024.100141
P. Moskal, et al., “Positronium image of the human brain in vivo,” Sci. Adv. 10(37), (2024). https://doi.org/10.1126/sciadv.adp2840
Copyright (c) 2025 Hawar M. Dlshad, Jamal M. Rashid

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