Mathematical modelling of formation of second tumours

Authors

  • V. G. Knigavko Kharkiv National Medical University image/svg+xml Author
  • E. B. Radzishevskaya Kharkiv National Medical University image/svg+xml Author
  • M. A. Bondarenko Kharkiv National Medical University image/svg+xml Author
  • O. S. Chubukin Kharkov National Medical University Author
  • T. R. Kocharova Kharkiv National Medical University image/svg+xml Author

Keywords:

mathematical modeling, cell malignization, second tumor, distribution function, probability density function

Abstract

The problem of second tumor formation causes the significant interest. The second tumor means that this
is the malignant tumor which will be forming after the treatment of the first one, and formation of second
tumor not connected with formation of the first one. The results of stochastic mathematical modeling
based on well known conception about damaging of any number of certain genes caused malignization of
cell was given. On the basis of these conceptions it is possible to solve the actual task - to build the
stochastic mathematical models which described characteristics of formation of the second tumor
(distribution function and probability density of these times).

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Author Biographies

  • V. G. Knigavko, Kharkiv National Medical University

    61022, Kharkov, Lenin av.,4

  • E. B. Radzishevskaya, Kharkiv National Medical University

    61022, Kharkov, Lenin av.,4

  • M. A. Bondarenko, Kharkiv National Medical University
    61022, Kharkov, Lenin av., 4
  • O. S. Chubukin, Kharkov National Medical University
    61022, Kharkov, Lenin av.,4
  • T. R. Kocharova, Kharkiv National Medical University
    61022, Kharkov, Lenin av.,4

Issue

Section

Biophysics of complex systems

How to Cite

Mathematical modelling of formation of second tumours. (2015). Biophysical Bulletin, 2(30). https://periodicals.karazin.ua/biophysvisnyk/article/view/2278

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