Cobalt and mercury chlorides action on lipid peroxidation indexes in blood serum and the resistance of the erythrocytes of rat females

Г. В. Ганусова
Т.В. Бараннік

Keywords: hemolysis; blood serum; erythrocytes; lipid peroxidation; cobalt chloride; mercury chloride

Abstract

Cobalt chloride and mercury chloride caused the accumulation of TBARS and heme-containing compounds in blood serum of rat females 2 hours after injection in vivo. The increase of lipid peroxidation products in neutral and phospholipid fractions of blood serum at cobalt ions action was revealed only at first hours and at mercury ions action – predominantly 24 hours after action. CoCl₂ caused the increase of peroxide resistance of erythrocytes both at 2 and 24 hours after treatment. 24 hours after injection of HgCl₂the increase of TBARS content and the decrease of protein concentration in blood serum were observed. These alterations in serum at HgCl₂action were accompanied by the increase of peroxide resistance of erythrocytes.

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References

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