ISCHEMIA EFFECT ON ATPASE ACTIVITY OF HEART MITOCHONDRIA IN YOUNG AND OLD RATS

  • V.N. Dzuba
  • Yu.V. Nikitchenko
  • T.A. Shmonina

Abstract

ATPase activity alterations in rats of different age groups during the total myocardial ischemia were studied. It was determined that only mitochondrial oligomycin-sensitive ATPase was sensitive to effect of the total myocardial ischemia. The fact that addition of magnesium ions in the incubation medium eliminated ischemic effect in 3-months old rats and weakened it in 24-months old rats pointed to important role of magnesium ions in structure-functional reconstruction of mitochondria under myocardial ischemia. Young 3months old rats were established to be more tolerant to myocardial ischemic damage thanold animals.

Downloads

Download data is not yet available.
How to Cite
Dzuba, V., Nikitchenko, Y., & Shmonina, T. (1). ISCHEMIA EFFECT ON ATPASE ACTIVITY OF HEART MITOCHONDRIA IN YOUNG AND OLD RATS. The Journal of V. N. Karazin Kharkiv National University, Series "Medicine", (1), 25-29. Retrieved from https://periodicals.karazin.ua/medicine/article/view/7450
Section
Fundamental research