Platelet aggregation assays at different temperatures

Authors

  • V. P. Berest Karazin Kharkiv National University Author
  • S. V. Gatash Karazin Kharkiv National University Author
  • O. T. Nikolov Karazin Kharkiv National University Author

Keywords:

platelet aggregation, temperature, light transmission aggregometry, temperature control

Abstract

In this paper, we describe thermomechanical changes in the standard instrument for the study of platelet
aggregation, which allow studying platelet function at temperatures different from ambient temperature.
Application of advanced aggregometer enables measurement of induced platelet aggregation at a
temperature range from 4 to 40 °C and use of the temperature dependence of aggregation data to intepret
mechanisms of platelet thermophysilogy. Perspectives and relevance of this approach for further inquiry
of platelet function at different temperatures is discussed particulrly pertaining to blood transfusion
practices and study of certain clinical situations.

Downloads

Download data is not yet available.

Author Biographies

  • V. P. Berest, Karazin Kharkiv National University

    4 Svobody Sq., 61077; berest@univer.kharkov.ua

  • S. V. Gatash, Karazin Kharkiv National University

    4 Svobody Sq., 61077; berest@univer.kharkov.ua

  • O. T. Nikolov, Karazin Kharkiv National University

    4 Svobody Sq., 61077; berest@univer.kharkov.ua

Issue

Section

Methods of biophysical investigations

How to Cite

Platelet aggregation assays at different temperatures. (2015). Biophysical Bulletin, 2(25). https://periodicals.karazin.ua/biophysvisnyk/article/view/2849

Most read articles by the same author(s)

1 2 3 4 > >>