Clinical and psychological features of patients with migraine without aura and chronic migraine

doi:10.26565/2312-5675-2018-10-05

Юрій Ігорович Романенко Lugansk State Medical University https://orcid.org/0000-0002-5193-4810
Ірина Анатолівна Григорова Kharkiv National Medical University https://orcid.org/0000-0002-2644-9880
Володимир Ігорович Романенко Family Medicine Institute, Kyiv https://orcid.org/0000-0002-0014-9660
Ірина Юріївна Романенко Ukrainian Scientific and Practical Center for Endocrine Surgery, Transplantation of Endocrine Organs and Tissues of the Ministry of Health of Ukraine https://orcid.org/0000-0002-0604-0156
Ігор Володимирович Романенко Lugansk State Medical University https://orcid.org/0000-0001-5724-8064

DOI: https://doi.org/10.26565/2312-5675-2018-10-05

Keywords: migraine, anxiety, depression, autonomic disorders, sleep disorders

Abstract

Migraine is the second most common after a tension-type headache and ranks third among all diseases that lead to a loss of performance among men and women under the age of 50 years.

The aim of the work was to study the prevalence and severity of manifestations of anxiety, depression, autonomic and dissomnical disorders in patients with migraine without aura and chronic migraine.

Material and methods. A total of 31 patients with diagnoses of migraine without aura (MwA) (group I, n = 20) and chronic migraine (CM) (group II, n = 11) were examined. The control group consisted of 30 healthy subjects. A clinical and neurological examination was carried out, experimental psychological methods included the Spielberger State and Trait Anxiety Inventory, Beck’s Depression Inventory, a questionnaire for determining autonomic disorders, a questionnaire for scoring the subjective characteristics of sleep.

Results.Patients with MwA and CM were characterized by significantly higher rates of state (SА) and trait (TА) anxiety, depression, more expressed signs of autonomic dysfunction and sleep disorders compared to healthy subjects. Patients with CM had significantly higher rates of SА (1.62 times), TА (1.26 times), subjective signs of depressive mood (1.21 times), sleep disorders (1,36 times)compared topatients with MwA, which can be considered as a factor in the chronicity of HA. In both clinical groups, statistically significant positive correlations were found between the Beck depression indicator and the TА indicator; in patients with MwA, there is a negative correlation between the sleep quality indicator and the autonomic dysfunction index and the Beck depression indicator.

Conclusions. For patients with MwA and CM were characterized significantly higher indices of SА and TА, depression, more pronounced signs of autonomic disorders and sleep disorders compared tohealthy subjects. Detected psycho-vegetative disorders are more common and more pronounced in patients with CM compared to patients with MwA. Determining the psycho-autonomicstate in this category of patients will allow us to individualize the approach to management and promptly developtreatment and rehabilitation modalities, if necessary, that will prevent the chronication of НА and help to improve the quality of life.

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References

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 // The Lancet. – Vol. 390(10100). –P.1211-1259.

Headache Classification Subcommittee of the IHS. The International Classification of Headache Disorders, 3rd edition // Cephalalgia. – 2018. – Vol. 38(1) – P.1–211.

Saylor D,Steiner TJ. The Global Burden ofHeadache / D. Saylor,TJ.Steiner // Semin Neurol. 2018. – Vol. 38, № 2. – Р.182-190. doi: 10.1055/s-0038-1646946. Epub 2018 May 23.

WorldHealthOrganization (WHO). Headache disorders. WHO fact sheet 277. Updated April 2016. http://www.who.int/mediacentre/factsheets/fs277/en/ Accessed February 21, 2018.

Осипова В.В. Первичные головные боли / В.В. Осипова, Г.Р. Табеева. - М.: Пагри-Принт, 2007. 58 с.

Odegard S.S. Associations between sleep disturbance and primary headaches: the third Nord-Trandelag Health Study / S.S. Odegard, M. Engstrom, T. Sand [et al.] // J. Headache Pain. – 2010. – Vol. 11, № 3. – P. 197-206.

Palacios-Ceña M. The association of headache frequency with pain interference and the burden of disease is mediated by depression and sleep quality, but not anxiety, in chronic tension type headache / M Palacios-Ceña, JJ Fernández-Muñoz, M Castaldo[et al.] //J Headache Pain. – 2017. –Vol. 18, № 1. – Р. 19. doi: 10.1186/s10194-017-0730-5.

Boardman H.F. Psychological, sleep, lifestyle, and comorbid associations with headache / H.F. Boardman, E. Thomas, D.S. Millson, P.R. Croft // Headache. – 2005. – Vol. 45, № 6. – P.657-669.

Lin YK. Associations Between Sleep Quality and Migraine Frequency: A Cross-Sectional Case-Control Study / YK Lin, GY Lin, JT Lee[et al.] // Medicine (Baltimore). – 2016. - Vol. 95, № 17. – e3554. doi: 10.1097/ MD.0000000000003554.

LlopSM. Increased prevalence of depression and anxiety in patients with migraine and interictal photophobia / SMLlop, JE Frandsen, KBDigre[et al.] // J Headache Pain. – 2016. - Vol. 17. – Р. 34. doi: 10.1186/s10194-016-0629-6.

BensenorI.M. Headache complaints associated with psychiatric comorbidity in a population-basedsample/ Bensenor, L.F. Tofoli, L. Andrade // BrazJMedBiolRes. – 2003. – Vol. 36. – P. 1425-32.

Cao M. Personality traits in migraine and tension-type headaches: a five-factor model study / M. Cao, S. Zhang, K. Wang // Psychopathology. – 2002. – Vol.35. – P. 254-8.

Esme Fuller-Thompson. Untangling the Associations Between Migraine, Pain, and Anxiety / Fuller-Thompson Esme, Jayanthikumar Janany, Agbeyaka K. Senyo // Headache. – 2017. - Vol. 57, № 3. – Р. 375 – 390.

PeresMFP. Anxiety and depression symptoms and migraine: a symptom-based approach research / MFP Peres, JPP Mercante, JPP Tobo PR[et al.] // J Headache Pain. – 2017. - Vol.18, № 1. – Р.37. doi: 10.1186/s10194-017-0742-1.

Breslau N. Comorbidity of migraine and depression: investigating potential etiology and prognosis / N. Breslau, R.B. Lipton, W.F. Stewart // Neurology. – 2003. – Vol.60.–P. 1308-12.

Mongini F. Personality traits, depression and migraine in women. A longitudinal study / F. Mongini, R. Keller, A. Deregibus // Cephalalgia. – 2003. – Vol. 23. – P. 186-92.

Leistad R.B. Stress induced pain and muscle activity in patients with migraine and tension type headache / R.B. Leistad, T. Sand, R.H. Westgaard et al // Cephalgia. – 2006. – Vol. 26 (1). – P. 64–73. doi: 10.1111/j.1468-2982.2005.00997.x.

ColmanIan. Migraine Headache and Risk of Selfharm and Suicide / Ian Colman, Mila Kingsbury, Jitender Sareen et al // Headache. – 2016. – Vol. 56, №1. –P. 132 –

MerikangasK.R. Migraineandpsychopathology. Results of the Zurich cohort study of young adults / K.R. Merikangas, J. Angst, H.Isler // Arch Gen Psychiatry. – 1990. – Vol. 47. – P.849-53.

Ханин Ю.Л. Исследование тревоги в спорте // Вопр. психологии. - 1978. – №6. – С.72-75.

Beck A.T. An inventory for measuring depression / A.T. Beck, C.H. Ward, M. Mendelson [et al.]// Arch Gen Psychiatry. – 1961. – Vol. 4. – P. 561–571.

Вегетативные расстройства. Клиника, диагностика, лечение / под редакцией А.М.Вейна. – М.: ООО «Медицинское информационное агентство», 2003. – 752с.

Вейн А.М. Синдром апноэ во сне и другие расстройства дыхания, связанные со сном: клиника, диагностика, лечение. / А.М. Вейн, Т.С. Елигулашвили, М.Г. Полуэктов. – М.: Эйдос Медиа, 2002. – 310 с.