PERMEABILITY OF BLOOD BRAIN BARRIER FOR CARDIOTROPIC SUBSTANCES UNDER HYPOTHERMIA AND HYPERTENSION

  • V.G. Babijchuk

Abstract

It has been shown that under hypothermia conditions the interactions between central and autonomous contours of cardiac activity regulation can be significantly changed, therefore the probability of paradoxical reactions of an organism to application of cardiotropic preparations increases. The change of a sign of chronotropic effect of cathecholamines (CA) and acethylcholine (AC) under hypothermia in a great extent is substantiated by an increase of blood brain barrier (BBB) permeability, that should be taken for consideration in practical medicine. Besides therapeutic cooling regimens contribute to a recovery of impaired rhythmicity of functioning of nerve and cardiovascular systems, in particular under conditions of emotional stress, that is one main causes of human disease appearing.

Downloads

Download data is not yet available.
How to Cite
Babijchuk, V. (1). PERMEABILITY OF BLOOD BRAIN BARRIER FOR CARDIOTROPIC SUBSTANCES UNDER HYPOTHERMIA AND HYPERTENSION. The Journal of V. N. Karazin Kharkiv National University, Series "Medicine", (1), 16-21. Retrieved from https://periodicals.karazin.ua/medicine/article/view/7448
Issue
No. 1 (2000)
Section
Fundamental research

The Journal of V. N. Karazin Kharkiv National University, series Medicine has following copyright terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work, with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.