PRE-HOSPITAL THROMBOLYSIS: STATUS OF PROBLEM
Keywords:
pre-hospital thrombolysis therapy, heart attack of myocardium
Abstract
The article summarizes the available data of clinical trials, registries and current guidelines about reperfusion therapy in patients with acute coronary syndromes with ST-segment elevation on electrocardio-gram. There were considered the role and place percutaneous coronary procedures and pre-hospital thrombolysis in medical care system in such patients. Pre-hospital thrombolysis can considered as method of choice in our country and it must be supplemented with system or rescue percutaneous coronary intervention.
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References
1. Карлов С.М., Целуйко В.И., Колиушко Г.И., и др. Эффективность тромболитической терапии в остром периоде инфаркта миокарда у больных пожилого и старческого возраста / Карлов С.М., Целуйко В.И., Колиушко Г.И., и др. // http://thrombolysis.org.ua/education/articles/thrombolytic-ami-eldery
2. В.М. Коваленко. Профілактика та лікування інфаркту міокарда в Україні / В.М. Коваленко. // http://www.ukrcardio.org/journal.php/article/373
3. Andersen H. A comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction / Andersen H., Nielsen T., Rasmussen K., [et al], for the DANAMI-2 Investigators // New Engl J Med. – 2003. – Vol.349 –P.733-742.
4. Antman E.M. 2007 Focused Update of the ACC/AHA 2004 Guidelines for the Management of Patients with ST-Elevation Myocardial Infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the Canadian Cardiovascular Society endorsed by the American Academy of Family Physicians: 2007 Writing Group to Review New Evidence and Update the ACC/AHA 2004 Guidelines, for the Management of Patients With ST-Elevation Myocardial Infarction, Writing on Behalf of the 2004 Writing Committee/ Antman E.M., Hand M., Armstrong P.W, [et al] // Circulation. – 2008. –Vol.117. – P.296-329.
5. Armstrong P., WEST Steering Committee. A comparison of pharmacologic therapy with/without timely coronary intervention vs. primary percutaneous intervention early after ST-elevation myocardial infarction: the WEST (Which Early ST-elevation myocardial infarction Therapy) study/ Armstrong P. // Eur Heart J. –2006. – Vol.27. –P.1530-1538.
6. Arntz H.R., European Resuscitation Council Guidelines for Resuscitation 2005. Section 5. Initial management of acute coronary syn¬dromes / Arntz H.R., Bossaert L., Filippatos G.// Resuscitation. – 2005. – Vol. 6751 – P.587-596.
7. Bassand J.P. Implementation of reperfusion therapy in acute myocardial infarction. A policy statement from the European Society of Cardiology/ Bassand J.P., Danchin N., Filippatos G., [et al]. // Eur Heart J. – 2005. –Vol.26 –P.2733-2741.
8. Bjorklund E. Prehospital thrombolysis delivered by para¬medics is associated with reduced time delay and mortality in ambulance-transported real-life patents with ST-elevation myocardial infarction / Bjorklund E., Stenestrand U., Lindback J., et al on behalf of the RIKS-HIA Investigators // Eur Heart J. – 2006. –Vol.27 – P.1146-1152.
9. Boersma E. Does time matter? A pooled analysis of randomized clinical trials comparing primary percutaneous cor¬onary intervention and in-hospital fibrinolysis in acute myocardial infarction / Boersma E., the PCAT-2 Trialists' Collaborative Group //Eur Heart J. – 2006 – Vol.27 – P.779-788.
10. Cambou J.P. The French registry of Acute ST elevation or non-ST-elevation Myocardial Infarction (FAST-MI): study design and baseline characteristics / Cambou J.P., Simon T., Mulak G. [et al]. //Arch Mai Coeur Vaiss. – 2007. –Vol.100- P.524-534.
11. Danchin N. Effect of reperfusion therapy on long-term outcome in patients>70 years of age / Danchin N., Angioi M., Demicheli T., [et al]. // Am J Cardiol. – 2002. – Vol.90 – P.1142-1145.
12. Danchin N., Blanchard D., Steg P., et al, for the USIC Investigators. lmpact of prehospital thrombolysis for acute myocardial infarction on 1-year outcome / Danchin N., Blanchard D., Steg P., [et al], for the USIC Investigators. // Circulation. – 2004 – Vol.110 – P.1909-1915.
13. Danchin N. Comparison of thrombolysis followed by broad use of percutaneous coron¬ary intervention with primary percutaneous coronary intervention for ST-segment-elevation acute myocardial infarction. Data from the French Registry on Acute ST-Elevation Myocardial Infarction (FAST-MI) / Danchin N., Coste P., Fejrieres J., [et al], for the FAST-MI Investigators. // Circulation. – 2008 – Vol.118 – P. 268-276.
14. Danchin N. Pre-hospital thrombolysis in perspective./ Danchin N., Durand E., Blanchard // European Heart Journal. -2008. – Vol.29, N.23. – P.2835-2842.
15. Danchin N. Treat¬ment of acute myocardial infarction by primary coronary angioplasty or intrave¬nous thrombolysis in the 'real world': one-year results from a nationwide French survey/ Danchin N., Vaur L., Genes N., [et al] // Circulation. – 1999. –Vol.99 – P.2639-2644.
16. de Boer M.J. Reperfusion therapy in elderly patients with acute myocardial infarction. A randomized comparison of primary angioplasty and thrombolytic therapy / de Boer M.J., Otteranger J.P., van't Hof A.W.J., [et al.] / de Boer M.J., Otteranger J.P., van't Hof A.W.J., [et al]. // J Am Coll Cardiol. – 2002. –Vol.39 – P.1723-1728.
17. Di Mario C. lmmediate angioplasty versus standard therapy with rescue angioplasty after thrombolysis in the Combined Abciximab REteplase Stent Study in Acute Myocardial Infarction (CARESS-in-AMI): an open, prospective, randomised, multicentre trial / Di Mario C., Dudek D., Piscione F., [et al], on behalf of the CARESS-in-AMI investigators. // Lancet.- 2008. –Vol.371 – P.559-568.
18. Eagle K.A. Global Registry of Acute Cor¬onary Events (GRACE) InvestigatorsTrends in acute reperfusion therapy for ST-segment elevation myocardial infarction from 1999 to 2006: we are getting better but we have got a long way to go / Eagle K.A., Nallamothu B.K., Mehta R.H., [et al]. // Eur Heart J. – 2008. – Vol.29 – P.609-617.
19. Fernandez-Aviles F. Routine invasive strategy within 24 hours of thrombo¬lysis versus ischaemia-guided conservative approach for acute myocardial infarc¬tion with ST-segment elevation (GRACIA-1): a randomised controlled trial / Fernandez-Aviles F., Alonso J.J., Castro-Beiras A., [et al]. // Lancet. – 2004. – Vol.364. – P.1045-1053.
20. Fox K. Decline in rates of death and heart failure in acute coronary syndromes, 1999-2006 / Fox K., Steg P., Eagle K., et al, for the GRACE Investigators. // JAMA. – 2007. – Vol.297. – P.1892-1900.
21. Henry T.D. A regional system to provide timely access to percutaneous coronary intervention for ST-elevation myocardial infarction / Henry T.D., Sharkey S.W., Burke N., [et al]. //Circulation. – 2007. – Vol.116- P.721-728.
22. Kalla K. lmplementation of guidelines improves the standard of care. The Viennese Registry on Reperfusion Strategies in ST-Elevation Myocardial Infarction (Vienna STEMI Registry) / Kalla K., Christ G., Karnik R., et al, for the Vienna STEMI Registry Group. // Circulation. – 2006. – Vol.113- P.2398-2405.
23. Keeley E. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials / Keeley E., Boura J., Grines C. // Lancet. – 2003.-Vol.361 –P.13-20.
24. McNamara R. Effect of door-to-balloon time on mortality in patients with ST-segment elevation myocar¬dial infarction / McNamara R., Wang Y., Herrin J., [et al], for the NRMI Investigators. // J Am Coll Cardiol. – 2006. – Vol.47 – P.45-51.
25. Morrison L. Mortality and prehospital thrombolysis for acute myocardial infarction. A meta-analysis / Morrison L., Verbeek P., McDonald A., [et al]. // JAMA. –Vol. 2000. –Vol.283 –P.2686-2692.
26. Nallamothu B. Times to treatment in transfer patients undergoing primary percuta¬neous coronary intervention in the United States. National Registry of Myocardial Infarction (NRMI)-3/4 Analysis / Nallamothu B., Bates E., Herrin J., [et al], for the NRMI Investigators. // Circulation. – 2005. – Vol.111 – P.761-767.
27. Price L. A quality study of paramedics' attitudes to providing prehospital thrombolysis / Price L., Keeling P., Brown G., [et al]. // Emerg Med J. – 2005. – Vol.22 – P.738-741.
28. Simon T. lmpact of age and gender on in-hospital and late mortality after acute myocardial infarc¬tion: increased early risk in younger women. Results form the French nation-wide USIC registries / Simon T., Магу-Krause M., Cambou J.P., [et al], on behalf of the USIC Investigators. //Eur Heart J. – 2006. – Vol.27. – P.1282-1288.
29. lmpact of time to treatment on mortality after prehospital fibrinolysis or primary angioplasty / Steg G., Bonnefoy E., Chabaud S., [et al], for the Comparison of Angioplasty Prehospital Thrombolysis In acute Myocardial infarction (CAPTIM) Investigators // Circu¬lation. – 2003. -Vol.108 –P.2851-2856.
30. Stenestrand U. Long-term outcome of primary percutaneous coronary intervention vs prehospital and in-hospital thrombolysis for patients with ST-elevation myocardial infarction / Stenestrand U., Lindback J., Wallentin L., for the RIKS-HIA Registry. // JAMA. – 2006. – Vol.296. – P.1749-1756.
31. Van de Werf F. The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology. Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation / Van de Werf F., Bax J., Betriu A., [et al]. //EHJ.- 2008. –Vol.29. –P.2909-2945.
32. Widimsky P. Long distance transport for primary angioplasty vs immediate thromboly¬sis in acute myocardial infarction. Final results of the randomized national multicentre trial—PRAGUE-2 / Widimsky P., Budesmsky T., Vorac D., [et al], on behalf of the PRAGUE Study Group Investigators // Eur Heart J. – 2003. – Vol.24. – P.94-104.
33. Zahn R. Primary angioplasty versus intravenous thrombolysis in acute myocardial infarction: can we define subgroups of patients benefiting most from primary angioplasty? Results from the pooled data of the maximal individual therapy in acute myocardial infarction registry and the myocardial infarction registry/ Zahn R., Schiele R., Schneider S., [et al], for the Maximal Individual Therapy in Acute Myocardial Infarction (MITRA) the Myocardial Infarction Regis¬try (MIR) Study Groups. // J. Am. Coll. Cardiol. – 2001. – Vol.37. – P.1827-1835.
2. В.М. Коваленко. Профілактика та лікування інфаркту міокарда в Україні / В.М. Коваленко. // http://www.ukrcardio.org/journal.php/article/373
3. Andersen H. A comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction / Andersen H., Nielsen T., Rasmussen K., [et al], for the DANAMI-2 Investigators // New Engl J Med. – 2003. – Vol.349 –P.733-742.
4. Antman E.M. 2007 Focused Update of the ACC/AHA 2004 Guidelines for the Management of Patients with ST-Elevation Myocardial Infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the Canadian Cardiovascular Society endorsed by the American Academy of Family Physicians: 2007 Writing Group to Review New Evidence and Update the ACC/AHA 2004 Guidelines, for the Management of Patients With ST-Elevation Myocardial Infarction, Writing on Behalf of the 2004 Writing Committee/ Antman E.M., Hand M., Armstrong P.W, [et al] // Circulation. – 2008. –Vol.117. – P.296-329.
5. Armstrong P., WEST Steering Committee. A comparison of pharmacologic therapy with/without timely coronary intervention vs. primary percutaneous intervention early after ST-elevation myocardial infarction: the WEST (Which Early ST-elevation myocardial infarction Therapy) study/ Armstrong P. // Eur Heart J. –2006. – Vol.27. –P.1530-1538.
6. Arntz H.R., European Resuscitation Council Guidelines for Resuscitation 2005. Section 5. Initial management of acute coronary syn¬dromes / Arntz H.R., Bossaert L., Filippatos G.// Resuscitation. – 2005. – Vol. 6751 – P.587-596.
7. Bassand J.P. Implementation of reperfusion therapy in acute myocardial infarction. A policy statement from the European Society of Cardiology/ Bassand J.P., Danchin N., Filippatos G., [et al]. // Eur Heart J. – 2005. –Vol.26 –P.2733-2741.
8. Bjorklund E. Prehospital thrombolysis delivered by para¬medics is associated with reduced time delay and mortality in ambulance-transported real-life patents with ST-elevation myocardial infarction / Bjorklund E., Stenestrand U., Lindback J., et al on behalf of the RIKS-HIA Investigators // Eur Heart J. – 2006. –Vol.27 – P.1146-1152.
9. Boersma E. Does time matter? A pooled analysis of randomized clinical trials comparing primary percutaneous cor¬onary intervention and in-hospital fibrinolysis in acute myocardial infarction / Boersma E., the PCAT-2 Trialists' Collaborative Group //Eur Heart J. – 2006 – Vol.27 – P.779-788.
10. Cambou J.P. The French registry of Acute ST elevation or non-ST-elevation Myocardial Infarction (FAST-MI): study design and baseline characteristics / Cambou J.P., Simon T., Mulak G. [et al]. //Arch Mai Coeur Vaiss. – 2007. –Vol.100- P.524-534.
11. Danchin N. Effect of reperfusion therapy on long-term outcome in patients>70 years of age / Danchin N., Angioi M., Demicheli T., [et al]. // Am J Cardiol. – 2002. – Vol.90 – P.1142-1145.
12. Danchin N., Blanchard D., Steg P., et al, for the USIC Investigators. lmpact of prehospital thrombolysis for acute myocardial infarction on 1-year outcome / Danchin N., Blanchard D., Steg P., [et al], for the USIC Investigators. // Circulation. – 2004 – Vol.110 – P.1909-1915.
13. Danchin N. Comparison of thrombolysis followed by broad use of percutaneous coron¬ary intervention with primary percutaneous coronary intervention for ST-segment-elevation acute myocardial infarction. Data from the French Registry on Acute ST-Elevation Myocardial Infarction (FAST-MI) / Danchin N., Coste P., Fejrieres J., [et al], for the FAST-MI Investigators. // Circulation. – 2008 – Vol.118 – P. 268-276.
14. Danchin N. Pre-hospital thrombolysis in perspective./ Danchin N., Durand E., Blanchard // European Heart Journal. -2008. – Vol.29, N.23. – P.2835-2842.
15. Danchin N. Treat¬ment of acute myocardial infarction by primary coronary angioplasty or intrave¬nous thrombolysis in the 'real world': one-year results from a nationwide French survey/ Danchin N., Vaur L., Genes N., [et al] // Circulation. – 1999. –Vol.99 – P.2639-2644.
16. de Boer M.J. Reperfusion therapy in elderly patients with acute myocardial infarction. A randomized comparison of primary angioplasty and thrombolytic therapy / de Boer M.J., Otteranger J.P., van't Hof A.W.J., [et al.] / de Boer M.J., Otteranger J.P., van't Hof A.W.J., [et al]. // J Am Coll Cardiol. – 2002. –Vol.39 – P.1723-1728.
17. Di Mario C. lmmediate angioplasty versus standard therapy with rescue angioplasty after thrombolysis in the Combined Abciximab REteplase Stent Study in Acute Myocardial Infarction (CARESS-in-AMI): an open, prospective, randomised, multicentre trial / Di Mario C., Dudek D., Piscione F., [et al], on behalf of the CARESS-in-AMI investigators. // Lancet.- 2008. –Vol.371 – P.559-568.
18. Eagle K.A. Global Registry of Acute Cor¬onary Events (GRACE) InvestigatorsTrends in acute reperfusion therapy for ST-segment elevation myocardial infarction from 1999 to 2006: we are getting better but we have got a long way to go / Eagle K.A., Nallamothu B.K., Mehta R.H., [et al]. // Eur Heart J. – 2008. – Vol.29 – P.609-617.
19. Fernandez-Aviles F. Routine invasive strategy within 24 hours of thrombo¬lysis versus ischaemia-guided conservative approach for acute myocardial infarc¬tion with ST-segment elevation (GRACIA-1): a randomised controlled trial / Fernandez-Aviles F., Alonso J.J., Castro-Beiras A., [et al]. // Lancet. – 2004. – Vol.364. – P.1045-1053.
20. Fox K. Decline in rates of death and heart failure in acute coronary syndromes, 1999-2006 / Fox K., Steg P., Eagle K., et al, for the GRACE Investigators. // JAMA. – 2007. – Vol.297. – P.1892-1900.
21. Henry T.D. A regional system to provide timely access to percutaneous coronary intervention for ST-elevation myocardial infarction / Henry T.D., Sharkey S.W., Burke N., [et al]. //Circulation. – 2007. – Vol.116- P.721-728.
22. Kalla K. lmplementation of guidelines improves the standard of care. The Viennese Registry on Reperfusion Strategies in ST-Elevation Myocardial Infarction (Vienna STEMI Registry) / Kalla K., Christ G., Karnik R., et al, for the Vienna STEMI Registry Group. // Circulation. – 2006. – Vol.113- P.2398-2405.
23. Keeley E. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials / Keeley E., Boura J., Grines C. // Lancet. – 2003.-Vol.361 –P.13-20.
24. McNamara R. Effect of door-to-balloon time on mortality in patients with ST-segment elevation myocar¬dial infarction / McNamara R., Wang Y., Herrin J., [et al], for the NRMI Investigators. // J Am Coll Cardiol. – 2006. – Vol.47 – P.45-51.
25. Morrison L. Mortality and prehospital thrombolysis for acute myocardial infarction. A meta-analysis / Morrison L., Verbeek P., McDonald A., [et al]. // JAMA. –Vol. 2000. –Vol.283 –P.2686-2692.
26. Nallamothu B. Times to treatment in transfer patients undergoing primary percuta¬neous coronary intervention in the United States. National Registry of Myocardial Infarction (NRMI)-3/4 Analysis / Nallamothu B., Bates E., Herrin J., [et al], for the NRMI Investigators. // Circulation. – 2005. – Vol.111 – P.761-767.
27. Price L. A quality study of paramedics' attitudes to providing prehospital thrombolysis / Price L., Keeling P., Brown G., [et al]. // Emerg Med J. – 2005. – Vol.22 – P.738-741.
28. Simon T. lmpact of age and gender on in-hospital and late mortality after acute myocardial infarc¬tion: increased early risk in younger women. Results form the French nation-wide USIC registries / Simon T., Магу-Krause M., Cambou J.P., [et al], on behalf of the USIC Investigators. //Eur Heart J. – 2006. – Vol.27. – P.1282-1288.
29. lmpact of time to treatment on mortality after prehospital fibrinolysis or primary angioplasty / Steg G., Bonnefoy E., Chabaud S., [et al], for the Comparison of Angioplasty Prehospital Thrombolysis In acute Myocardial infarction (CAPTIM) Investigators // Circu¬lation. – 2003. -Vol.108 –P.2851-2856.
30. Stenestrand U. Long-term outcome of primary percutaneous coronary intervention vs prehospital and in-hospital thrombolysis for patients with ST-elevation myocardial infarction / Stenestrand U., Lindback J., Wallentin L., for the RIKS-HIA Registry. // JAMA. – 2006. – Vol.296. – P.1749-1756.
31. Van de Werf F. The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology. Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation / Van de Werf F., Bax J., Betriu A., [et al]. //EHJ.- 2008. –Vol.29. –P.2909-2945.
32. Widimsky P. Long distance transport for primary angioplasty vs immediate thromboly¬sis in acute myocardial infarction. Final results of the randomized national multicentre trial—PRAGUE-2 / Widimsky P., Budesmsky T., Vorac D., [et al], on behalf of the PRAGUE Study Group Investigators // Eur Heart J. – 2003. – Vol.24. – P.94-104.
33. Zahn R. Primary angioplasty versus intravenous thrombolysis in acute myocardial infarction: can we define subgroups of patients benefiting most from primary angioplasty? Results from the pooled data of the maximal individual therapy in acute myocardial infarction registry and the myocardial infarction registry/ Zahn R., Schiele R., Schneider S., [et al], for the Maximal Individual Therapy in Acute Myocardial Infarction (MITRA) the Myocardial Infarction Regis¬try (MIR) Study Groups. // J. Am. Coll. Cardiol. – 2001. – Vol.37. – P.1827-1835.
How to Cite
Kopytsa, N., Tytarenko, N., & Belaya, N. (1). PRE-HOSPITAL THROMBOLYSIS: STATUS OF PROBLEM. The Journal of V. N. Karazin Kharkiv National University, Series "Medicine", (18), 64-73. Retrieved from https://periodicals.karazin.ua/medicine/article/view/6958
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