HEART RATE VARIABILITY PARAMETERS IN PATIENTS WITH ARTERIAL HYPERTENSION IN DEPENDENCE ON THE TYPE OF DAILY BLOOD PRESSURE PROFILE
Abstract
Violation of functioning of the autonomic nervous system is an important factor in the formation and progression of arterial hypertension (AH). Abnormal nocturnal blood pressure (BP) reduction is regarded as an independent prognostic factor for cardiovascular complications in patients with AH. One of the possible factors that determine the violation of BP circadian rhythm can be imbalance of different parts of autonomic nervous system.
The aim of our study was to study heart rate variability (HRV) in patients with AH, dependently of BP profile. 72 patients with AH were examined. Average age was 57 ± 11 years.
All patients underwent ambulatory BP (ABPM) and ECG monitoring. To define the daily profile the nocturnal BP dip was quantified and for HRV evaluation the frequency analysis method was used. HRV changes in patients with AH present with reduced total power and with a violation in the ratio of the powers of very low, low and high frequencies, enhanced sympathycotension and influence of humoral factors. Violations of systolic BP (SBP) daily profile was mainly characterized by an increase in the power of low frequency waves, which indicates an intensification of sympathetic and decreased parasympathetic influences. Violations of diastolic BP (DBP) daily profile were mainly characterized by a relative increase in the power of very low frequency waves. The obtained results showed that in the management of patients with AH it is important not only to control the circadian SBP and DBP profiles, but the evaluation of HRV also.
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References
Global Disparities of Hypertension Prevalence and Control: A Systematic Analysis of Population-Based Studies From 90 Countries. / [K. T. Mills, J. D. Bundy, T. N. Kelly et al.]. // Circulation. – 2016. –No 134. – p. 441–450.
Martynenko A.V. Heart rate variability: classification and dynamic system analysis / A.V. Martynenko, M.I. Yabluchansky // Journal of V. N. Karazin` KhNU, Series «Medicine».– 2005. – Issue 11. – P. 10–18.
Schmidt E. Yu. Closed loop biofeedback of heart rate variability and paced breathing efficacy evaluation in patients with arterial hypertension / E. Yu. Schmidt, A. L. Kulyk, A.V. Martynenko [et al.] // Journal of V. N. Karazin` KhNU, Series «Medicine». – 2011. – Issue 22. – P. 63–67.
Tominа О. E. Heart rate variability in patients with hypertension, comorbid with peptic ulcer disease, taking into account circadian systolic blood pressure / О. E. Tominа, O. Yu. Bichkova, G. M. Fomych [et al.] //Journal of V. N. Karazin` KhNU, Series «Medicine». – 2012. – Issue 24. – P. 52–62. Journal of V. N. Karazin` KhNU. 2017 22
Golubkina E. O. Assessment of changes in the distribution ratios of ultra-low-frequency, low-frequency and high-frequency components of heart rate variability during the paced breathing test in patients with arterial hypertension /E. O. Golubkina, O. O. Golubkina // Journal of V.N. Karazin` KhNU, Series «Medicine». – 2016. – Issue 31. – P. 10–17.
2013 ambulatory blood pressure recommendations for the Diagnosis of Adult Hypertension, Assessment of Cardiovascular and other Hypertension-associated Risk and Attainment of Therapeutic Goals / [R. C. Hermida, M. H. Smolensky, D. E. Ayala et al.] // Chronobiology International. – 2013. –No 30. –p. 55–410.
Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. // Circulation. – 1996. –No 93. – p. 1043–1065.
Singh J. P. Reduced Heart Rate Variability and New-Onset Hypertension. Insights Into Pathogenesis of Hypertension: The Framingham Heart Study / Jagmeet P. Singh, Martin G. Larson, Hisako Tsuji [et al.] // Hypertension. – 1998 – Issue 32. – P. 293–297.
Carthy E. R. Autonomic dysfunction in essential hypertension: A systematic review. / Elliott R. Carthy // Annals of Medicine and Surgery. – 2014. – Issue 3. – P. 2–7.
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