THE METABOLIC ACTIVITY OF MEDULLAR CELLS AT STAGES OF HAEMOPOESIS RECOVERING OF THE ANIMALS AFTER IRRADIATIATION AND MYELOTRANSPLANTATION
Keywords:
metabolism, marrow, transplantation
Abstract
The intensity of myelocariocytes metabolism from the tenth day after lethal irradiation of mice till the ninetieth and transplantation of medullar cells was studied. The activity of energetic metabolic enzymes and the state of the lipid peroxidation - antioxidation protection system of myelocaryocytes was investigated. It was shown that a significant activity increase of myelocaryocytes enzymes took place at the stage of medullar cells recovery. At the same time the activation of lipid peroxidation processes is accompanied by an increase of antioxidant resources enabling effective control of free-radical oxidation in medullar cells.
Downloads
Download data is not yet available.
References
1. Астауров Б.Л. Методы биологии развития М.:Наука. 1974. С. 349-350.
2. Powell W.S. Chromatography of Lipids for Biomedicine Research and Clinical Diagnostic. // Amsterdam: Elsev. Sci. Publ. 1987. P. 76-106.
3. Спиричев В.Б., Матусис И.И., Бронштейн Л.М. Экспериментальная витаминология. Минск: Наука и техника. 1979. С. 20-57.
4. Паранич Л.И., Паранич А.В., Василенко Н.М., Бугай Е.В. Действие нитробензола и его хлорпроиз-водных на некоторые показатели антиокислительного гомеостаза в тканях крыс //Бюлл. эксперим. биол. и мед. 1993. №10. С. 402-405.
5. Паранич А.В. Кониасо А., Бугай Е.В., Копылов А.В. О роли жирорастворимых витаминов А и Е в профилактике биологических эффектов ионизирующего излучения в различных тканях крыс //Радиобиология. 1992. Т.32. Вып.5. С.743-750.
2. Powell W.S. Chromatography of Lipids for Biomedicine Research and Clinical Diagnostic. // Amsterdam: Elsev. Sci. Publ. 1987. P. 76-106.
3. Спиричев В.Б., Матусис И.И., Бронштейн Л.М. Экспериментальная витаминология. Минск: Наука и техника. 1979. С. 20-57.
4. Паранич Л.И., Паранич А.В., Василенко Н.М., Бугай Е.В. Действие нитробензола и его хлорпроиз-водных на некоторые показатели антиокислительного гомеостаза в тканях крыс //Бюлл. эксперим. биол. и мед. 1993. №10. С. 402-405.
5. Паранич А.В. Кониасо А., Бугай Е.В., Копылов А.В. О роли жирорастворимых витаминов А и Е в профилактике биологических эффектов ионизирующего излучения в различных тканях крыс //Радиобиология. 1992. Т.32. Вып.5. С.743-750.
How to Cite
Romanova, E. (1). THE METABOLIC ACTIVITY OF MEDULLAR CELLS AT STAGES OF HAEMOPOESIS RECOVERING OF THE ANIMALS AFTER IRRADIATIATION AND MYELOTRANSPLANTATION. The Journal of V. N. Karazin Kharkiv National University, Series "Medicine", (2), 108-112. Retrieved from https://periodicals.karazin.ua/medicine/article/view/7444
Issue
Section
Clinical research
The Journal of V. N. Karazin Kharkiv National University, series Medicine has following copyright terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work, with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
