THE INFLUENCE OF CHLOROPHYLLIPTUM ON IMMUNOPATHOGENETIC INFLAMMATION FACTORS IN PURULENT RHINOSINUSITIS PATIENTS SUFFERING FROM INSULAR DIABETES MELLITUS

  • N.N. Popov
  • E.V. Ognivenko
  • E.A. Romanova
Keywords: chlorophylliptum, cytokines, circulating immune complexes, autoantibodies, rhinosinu-sitis, diabetes mellitus

Abstract

The efficiency of administration of chlorophylliptum as an immunomodulator as well as that of applica-tion of essentiale and potassium orotatum for compensation of the pathogenetic immunity link malfunctions in purulent rhinosinusitis patients suffering from insular diabetes has been investigated in our work. Under the influence of introduced therapy considerable reduction of superoxide radical exoproduction by cells, reduction of proinflammatory cytokine content in blood serum (interleucin-1β, interleucin-6, tumor necrosis factor-α) and dynamic reduction of tissue-aggressive factor content in blood serum (average and small molecular circulating immune complexes, autoantibodies to collagen and elastin) have been observed.

Downloads

Download data is not yet available.

References

1. Лыков А. П., Сахнов Л. В., Козлов В. А. // Иммунология. - 1998. - № 1. - С. 57-59.

2. Огнивенко Е. В., Попов Н. Н., Романова Е. А. // Вісник ХНУ імені В. Н. Каразіна, серія «Медици-на». - 2008. - № 797, вип. 15. - С. 110-114.

3. Попов Н. Н., Огнивенко Е. В., Романова Е. А. // Проблеми медичної науки та освіти. - 2007. - № 1. - С. 26–28.

4. Попов Н. Н., Огнивенко Е. В., Романова Е. А. // Вісник невідкладної і відновної медицини. - 2008. - Т. 9, № 2. - С. 202-205.

5. Филатова Г.А., Попкова А.М., Гришина Т.И. // Иммунология. - 2005. - № 4. - С. 205-208.

6. Фролов В.М., Пинский Л.Л., Пересадин Н.А. // Пробл. эндокринол. - 1991. - № 5. - С. 22-24.

7. Ahsan H., Ali A., Ali R. // Clin. Exp. Immunol. - 2003. - Vol. 131. - № 3. - P. 398-404.

8. Borregaard N., Theigaard-Monh K. et al // Curr. Opin. Hematol. - 2001. - Vol. 8. - № 1. - P. 23-27.

9. Clouter A., McDonald P.P. // Chem. Immunol. Allergy. - 2003. - Vol. 83. - P. 1-23.
How to Cite
Popov, N., Ognivenko, E., & Romanova, E. (1). THE INFLUENCE OF CHLOROPHYLLIPTUM ON IMMUNOPATHOGENETIC INFLAMMATION FACTORS IN PURULENT RHINOSINUSITIS PATIENTS SUFFERING FROM INSULAR DIABETES MELLITUS. The Journal of V. N. Karazin Kharkiv National University, Series "Medicine", (16), 68-72. Retrieved from https://periodicals.karazin.ua/medicine/article/view/6988
Section
Clinical research

Most read articles by the same author(s)

1 2 > >>