THE INFLUENCE OF CHLOROPHYLLIPTUM ON IMMUNOPATHOGENETIC INFLAMMATION FACTORS IN PURULENT RHINOSINUSITIS PATIENTS SUFFERING FROM INSULAR DIABETES MELLITUS
Abstract
The efficiency of administration of chlorophylliptum as an immunomodulator as well as that of applica-tion of essentiale and potassium orotatum for compensation of the pathogenetic immunity link malfunctions in purulent rhinosinusitis patients suffering from insular diabetes has been investigated in our work. Under the influence of introduced therapy considerable reduction of superoxide radical exoproduction by cells, reduction of proinflammatory cytokine content in blood serum (interleucin-1β, interleucin-6, tumor necrosis factor-α) and dynamic reduction of tissue-aggressive factor content in blood serum (average and small molecular circulating immune complexes, autoantibodies to collagen and elastin) have been observed.
Downloads
References
2. Огнивенко Е. В., Попов Н. Н., Романова Е. А. // Вісник ХНУ імені В. Н. Каразіна, серія «Медици-на». - 2008. - № 797, вип. 15. - С. 110-114.
3. Попов Н. Н., Огнивенко Е. В., Романова Е. А. // Проблеми медичної науки та освіти. - 2007. - № 1. - С. 26–28.
4. Попов Н. Н., Огнивенко Е. В., Романова Е. А. // Вісник невідкладної і відновної медицини. - 2008. - Т. 9, № 2. - С. 202-205.
5. Филатова Г.А., Попкова А.М., Гришина Т.И. // Иммунология. - 2005. - № 4. - С. 205-208.
6. Фролов В.М., Пинский Л.Л., Пересадин Н.А. // Пробл. эндокринол. - 1991. - № 5. - С. 22-24.
7. Ahsan H., Ali A., Ali R. // Clin. Exp. Immunol. - 2003. - Vol. 131. - № 3. - P. 398-404.
8. Borregaard N., Theigaard-Monh K. et al // Curr. Opin. Hematol. - 2001. - Vol. 8. - № 1. - P. 23-27.
9. Clouter A., McDonald P.P. // Chem. Immunol. Allergy. - 2003. - Vol. 83. - P. 1-23.
The Journal of V. N. Karazin Kharkiv National University, series Medicine has following copyright terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work, with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.