POTENTIAL IMMUNOMODULATION ACTION OF PARTIAL ACYLATED INTERLEUKIN-2 IN EXPERIMENTS
Keywords:
blasttransformation, lymphocytes, immunostimulation, interleukin-2
Abstract
In the article were presented results about studied of immunopotential activity of new IL-2 – acylated derivatives. It was show, that preparation much increased spontaneous blasttransformation of lymphocytes in mice as in vitro and in vivo. Added of acIL-2 to lymphhocete’s cells culture resulted to more increasing of mitotic activity of lymphocytes than in control with native Roncoleukin.Downloads
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References
1. Попов Н.Н., Савченко В.Н., Моджекву Ч.Ч., Куринная Е.Г. Виды и средства иммунотерапии. - Ха-рьков: Гриф. - 2002. - С. 59.
2. Попов Н.Н., Лавров В.Ф., Солошенко Э.Н. Клиническая иммунология и алергология. -М.: Реинфор. - 2004. - С. 56-81.
3. Мartynov А.V., Smelyanskaya M.V. // J. of Interf. & Cytokine res. - 2005.- Vol. 25. - № 7. - P. 414-417.
2. Попов Н.Н., Лавров В.Ф., Солошенко Э.Н. Клиническая иммунология и алергология. -М.: Реинфор. - 2004. - С. 56-81.
3. Мartynov А.V., Smelyanskaya M.V. // J. of Interf. & Cytokine res. - 2005.- Vol. 25. - № 7. - P. 414-417.
How to Cite
Romanova, E., Martynov, A., Igumnova, N., Sidorenko, T., Chernyavsky, V., Smelyanskaya, M., & Peremot, S. (1). POTENTIAL IMMUNOMODULATION ACTION OF PARTIAL ACYLATED INTERLEUKIN-2 IN EXPERIMENTS. The Journal of V. N. Karazin Kharkiv National University, Series "Medicine", (13), 49-52. Retrieved from https://periodicals.karazin.ua/medicine/article/view/7077
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Fundamental research
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