THE FREQUENCY OF USE OF COMBINATIONS OF ANTIHYPERTENSIVE DRUGS IN PATIENTS WITH DIFFICULT-TO-CONTROL HYPERTENSION ON THE BACKGROUND OF BIOFEEDBACK AND PACED BREATHING AND HEART RATE VARIABILITY
Abstract
The frequency of administration of combinations of antihypertensive drugs and its changes at different stages of observation was studied in 60 patients with difficult-to-control arterial hypertension (DTCAH) (32 men and 28 women) aged 59.0 ± 9.4. All patients were randomly divided into two subgroups: biofeedback (BFB) in the loop of paced breathing (PB) and heart rate variability (HRV) (33 patients) – basic subgroup, subgroup of comparisons (27 patients). Determined that patients with DTCAH in the subgroup of patients with the BFB in the loop of PB there has been a reduction of four-component antihypertensive therapy to three-component and in the subgroup of comparisons the frequency of the appointment of a four-component therapy was increased. At the same time, it was found that the addition of drug therapy with regular BFB sessions in the loop of PB contributed to the potentiation of the antihypertensive effect in patients with DTCAH. It is concluded that the BFB in the loop of PB and HRV can be used as a technology to improve the efficiency of control of blood pressure in patients with DTCAH.
Downloads
References
Systolic and diastolic short-term blood pressure variability and its determinants in patients with controlled and uncontrolled hypertension: A retrospective cohort study / Martino F. Pengo, Giacomo Rossitto, Valeria Bisogni [et. al.] // Blood Pressure –2015. – No. 24 (2). – P. 124–129.
Muntner P, Davis BR, Cushman WC, Bangalore S, Calhoun DA, Pressel SL, et al. Treatment-resistant hypertension and the incidence of cardiovascular disease and end-stage renal disease: results from the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). Hypertension (2014) 64:1012–21.
ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) / Giuseppe Mancia, Robert Fagard, Krzysztof Narkiewicz [et al.]. // Journal of Hypertension. – 2013. – No. 31. – P. 1281–1187.
Unifikovaniy klinichniy protokol pervinnoyi, ekstrennoyi ta vtorinnoyi (spetsializovannoyi) dopomogi «Arterialna gipertenziya». – Praktichniy likar. – 2013. – No. 2. – stor.43–51).
Kulik A. L. Biofeedback and modern clinical practice. / A. L. Kulik, N. I. Yabluchanskiy // The Journal of V. N. Karazin Kharkiv National University. Series «Medicine». – 2011. – No. 22 (975). – P. 82–93.
Shmidt E. Yu. Closed loop biofeedback of heart rate variability and paced breathing efficacy evaluation in patients with arterial hypertension / E. Yu. Shmidt, A. L. Kulik, A. V. Martyinenko [et al.] // The Journal of V. N. Karazin Kharkiv National University. Series «Medicine». – 2011. – No. 22 (975). – P. 63–67.
Belal S. A. S. The influence of biofeedback sessions in closed loop of heart rate variability and paced breathing on systolic blood pressure control during standart drug therapy in patients with arterial hypertension / S. A. S. Belal, N. A. Vodyanitskaya, M. I. Yabluchanskiy // The Journal of V. N. Karazin Kharkiv National University. Series «Medicine». – 2015. – No. 29. – P. 11–21.
Copyright (c) 2018 The Journal of V. N. Karazin Kharkiv National University, series "Medicine"
This work is licensed under a Creative Commons Attribution 4.0 International License.
The Journal of V. N. Karazin Kharkiv National University, series Medicine has following copyright terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work, with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.