HYPERTENSIVE CRISES AND HEART RATE VARIABILITY OF HYPERTENSIVE PATIENTS
Abstract
The aim of the research was to study the heart rate variability indexes of hypertensive patients with crisis and crisisless idiopathic hypertensia. 176 hypertensive patients were examined. The obtained data confirmed the decrease of total HRV capacity of hypertensive patients in supine as well as in upright position, it was evidence of an increased risk of cardiovascular death-rate. The obtained data confirm the hypothesis that the dysregulation of autonomous nervous system becomes apparent not only in the decrease of parasympathetic but in sympathetic HRV indexes of hypertensive patients in comparison with healthy people at rest as well as in tilt-test. The unbalance of autonomous regulation was observed, it was displayed in weakening of sympathetic unit of reaction to orthostatic load. The activation of humoral regualtion mechanisms was revealed on the background of the activity decrease of autonomous nervous system of the hypertensive patients, it was reflected by an increase of VLF absolute value and increase of relative VLF input-components. The unbalance of autonomous nervous system of hypertensive patients was not connected to hypertensive crises and HRV indexes can not be used as the prognostic criteria of short-term fluctuations of pressure.
Downloads
References
2. N.M.Kaplan. Clinical Hypertension//7th Edition. 1998. 424 P.
3. Артерільна гіпертонія: сучані діагностичні та лікувальні підходи. / Під ред. В.О.Боброва. Львів.1998. 94 C.
4. Ponikowski P; Anker SD; Chua TP; Szelemej R; Piepoli M; Adamopoulos S; Webb-Peploe K; Harrington D; Banasiak W; Wrabec K; Coats; AJ. Depressed heart rate variability as an independent predictor of death in chronic congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.// Jun Am J Cardiol. 1997. V.15. № 79:12. Р. 1645-1650.
5. Dekker J.M., Schouten E.G., Klootwijk P. et al. Heart rate variability from short electrocardiographic recordings predicts mortality from all causes in middle-aged and elderly men. The Zutphen study // Am J Epidemiology. 1997. Mar. V. 15. № 145:10. P. 899-890.
6. Heart rate variability. Standarts of measurement, physiological interpretation and clinical use / Task force of The European Society of Cardiologyand The North American Society of Pacing and Electrophysiology // Europ Heart J. 1996. № 17. P. 354-381.
7. Singh JP, Larson MG, Tsuji H, Evans JC, O'Donnell CJ, Levy D. Reduced heart rate variability and new-onset hypertension: insights into pathogenesis of hypertension: the Framingham Heart Study.// Hypertension. 1998. Aug. V. 32(2). P. 293-297.
8. Liao D, Cai J, Barnes RW, Tyroler HA, Rautaharju P, Holme I, Heiss G. Association of cardiac autonomic function and the development of hypertension: the ARIC study.// Am J Hypertens. 1996. Dec. V. 9(12 Pt 1). P. 1147-1156.
9. Huikuri HV, Ylitalo A, Pikkujamsa SM, Ikaheimo MJ, Airaksinen KE, Rantala AO, Lilja M, Kesaniemi YA. Heart rate variability in systemic hypertension.// Am J Cardiol. 1996. May 15. V. 77(12). P. 1073-1077.
10. Guidelines Subcommittee. 1999 World Health Organization-International Society of Hypertension Guide-lines for the Management of Hypertension. //J Hypertens. 1999. № 17. Р. 151-183.
11. Гипертензивные кризы. Классификация рабочей группы Украинского общества кардиологов. Доктор. 2000. № 2. С. 32-34.
12. Radaelli A, Ricordi L, Corbellini D, Solda PL, Calciati A, Salvucci F, Marchesi E, Finardi G, Bernardi L [The variability of the heart rate, arterial pressure and peripheral circulation as the indices of autonomic control in essential hypertension].// Cardiologia. 1991. Dec. V.36(12). P. 961-969.
13. Kario K, Motai K, Mitsuhashi T, Suzuki T, Nakagawa Y, Ikeda U, Matsuo T, Nakayama T, Shimada K. Autonomic nervous system dysfunction in elderly hypertensive patients with abnormal diurnal blood pressure variation: relation to silent cerebrovascular disease.// Hypertension. 1997. Dec. V. 30(6). P. 1504-1510.
The Journal of V. N. Karazin Kharkiv National University, series Medicine has following copyright terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work, with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.