INFLUENCE OF В-LYMPHOCYTES ON BONE MARROW RECOVERY OF THE IRRADIATED RECIPIENTS OF ALLOGENIC MIELOTRANSPLANT
Abstract
The study of influencing of enriching allogenic mielotransplant by B-lymphocytes on recovery of hemopoiesis and immunogenesis of the irradiated recipients and possibility of development at them GVHD was the purpose of work. It is rotined that application of В-lymphocytes is joint with mielocariocytes renders a stimulant effect on renewal total organcellularity, number of CFU, lymphocytes of bone marrow of the lethally irradiated recipients. Adding of В-lymphocytes to allogenic T-depleted mielotransplant is instrumental in forming of tolerance to the donor cells and establishment of cellular chimerism.
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References
2. Davidson W.F., Parish C.R. // J.Immunol.Meth. - 1975. - Vol.7. - №2-3. - P. 291-300.
3. Till J.E., McCulloch E.A. // Radiation Res. - 1961. - Vol.14. - №12. - P. 213-233.
4. Получение хромосомных препаратов лимфоидных клеток / Иммунология: Практикум / Е.У. Па-стер, В.В. Овод, В.К. Позур, Н.Е. Вихоть. -К.:Выща школа. - 1989. - С. 254-264.
5. Pietrangeli C.E., Osmond D.G. // Cell Immunol. - 1987. - Vol.107. - №2. - P. 348-357.
6. Goldshneider J. // Cell Immunol. - 1976. - Vol. 24. - № 2. - P. 289-307.
7. Зарецкая Ю.М. Смешанная культура лимфоцитов / Клиническая иммуногенетика. -М.: Медицина. - 1983. - С.47-50.
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