Synthesis of acylmethanesulfonamides by Claisen reaction
DOI:
https://doi.org/10.26565/2220-637X-2016-27-07Keywords:
β-ketosulfonamides, Claisen condensation, 1-(methylsulfonyl)piperidineAbstract
A method of valuable building-blocks – N,N-disubstituted β–ketosulfonamides – synthesis was developed on the example of condensation of N,N-disubstituted methanesulfonamides with ethyl benzoate, methyl cinnamate and ethyl acetate by Claisen. It was shown, that when ethylacetate is used in investigated reaction the formation of ethyl acetoacetate occurs only in small amounts.
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