Identification of calcium-phosphate biomaterials based on characteristic ions in mass spectra
Keywords:
hydroxyapatite, plasma desorption mass spectrometry, ion formation, characteristic ionsAbstract
Hydroxyapatite is one of the best materials for the production or modification of orthopaedic implants; it
is also can be a part of synthetic composite materials for bone regeneration. Its biological activity is
caused by structural similarity to the inorganic part of bone (called often the non-stoichiometric
hydroxyapatite or bioapatite). Hydroxyapatite can be resorbed by the surrounding bone tissue and
replaced by a natural bone, which results in good bonding between the implant and tissue. There are a lot
of technologies to develop hydroxyapatite biomaterials. The advantages and limitations of each technique
should be studied individually; in every specific case one should take into account the properties of
resulting hydroxyapatite, its chemical purity, micro- and nanostructure, macroscopic structural features,
bone connectivity strength, biocompatibility. We have applied desorption mass spectrometry with the
ionization of sample by 252Cf fission fragments (PD MS) for the analysis of synthetic hydroxyapatite. The
ion species desorbed from the hydroxyapatite surface under fission fragment impacts were studied, and
three series of polyatomic ions have been detected, two of which had not been described in earlier in
literature.
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