UV-SPECTROSCOPY STUDY OF THE EFFECT OF TEMPERATURE ON HUMAN BLOOD PLATELETS

Authors

  • V. P. Berest Kharkov State University Author
  • T. F. Morozova Institute for Problems of Cryobiology and Cryomedicine, National A cademy of Sciences of Ukraine Author
  • S. V. Gatash Kharkov State University Author

Keywords:

platelet, aggregation, receptors, temperature, UV-speclroscopy

Abstract

The structural changes of human blood platelet proteins at temperatures from 6 to 40°C have been studied by using UV-spectroscopy method. The change of platelet shape has been found at 14-18°C when heated. This fact is probably connected to a rearrangement of the cytoskeleton and actin polymerisation. The structural changes of ADP and fibrinogen receptors of the platelet plasma membrane have been observed at 18-20°C and 30-32°C, as well. It has been supposed that these changes determine the features of the dependence of ADP-induced platelet aggregation on temperature.

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Author Biographies

  • V. P. Berest, Kharkov State University

     4 Smbody Sq., Kharkov 310077, Ukraine

  • T. F. Morozova, Institute for Problems of Cryobiology and Cryomedicine, National A cademy of Sciences of Ukraine

    23 Pereyaslavskaya St., Kharkov 310015, Ukraine

  • S. V. Gatash, Kharkov State University

     4 Smbody Sq., Kharkov 310077, Ukraine

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Issue

Vol. 2 No. 2 (1998): Біофізичний вісник

Section

Cell biophysics

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How to Cite

UV-SPECTROSCOPY STUDY OF THE EFFECT OF TEMPERATURE ON HUMAN BLOOD PLATELETS. (2015). Biophysical Bulletin, 2(2). https://periodicals.karazin.ua/biophysvisnyk/article/view/2449

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