ISCHEMIA EFFECT ON ATPASE ACTIVITY OF HEART MITOCHONDRIA IN YOUNG AND OLD RATS

Authors

  • V.N. Dzuba
  • Yu.V. Nikitchenko
  • T.A. Shmonina

Abstract

ATPase activity alterations in rats of different age groups during the total myocardial ischemia were studied. It was determined that only mitochondrial oligomycin-sensitive ATPase was sensitive to effect of the total myocardial ischemia. The fact that addition of magnesium ions in the incubation medium eliminated ischemic effect in 3-months old rats and weakened it in 24-months old rats pointed to important role of magnesium ions in structure-functional reconstruction of mitochondria under myocardial ischemia. Young 3months old rats were established to be more tolerant to myocardial ischemic damage thanold animals.

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Issue

No. 1 (2000)

Section

Fundamental research

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How to Cite

ISCHEMIA EFFECT ON ATPASE ACTIVITY OF HEART MITOCHONDRIA IN YOUNG AND OLD RATS. (2019). The Journal of V. N. Karazin Kharkiv National University, Series "Medicine", 1, 25-29. https://periodicals.karazin.ua/medicine/article/view/7450

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