ROLE OF NESFATIN-1 IN MAINTAINING CARBOHYDRATE HOMEOSTASIS IN HYPERTENSIVE PATIENTS

  • M. O. Vizir Kharkiv National Medical University, Kharkiv, Ukraine
  • O. M. Kovalyova Kharkiv National Medical University, Kharkiv, Ukraine
Keywords: nesfatin-1, insulin, hypertension, prediabetes, polymorbidity

Abstract

The aim of this study is to analyze changes in the nesfatin-1 level in hypertensive patients depending on the carbohydrate profile parameters. 83 hypertensive patients aged 33 to 77 years were examined. Nesfatin-1 levels were determined by enzyme immunoassay method. Hypertensive patients have significantly higher levels of adipocytokine than healthy people. Results of data analyses may indicate a possible antihyperglycemic and insulinotropic effect of nesfatin-1 in hypertensive patients with normoglycemia or prediabetes. Confirmation of these processes requires a special study.

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Author Biographies

M. O. Vizir, Kharkiv National Medical University, Kharkiv, Ukraine

61022, Kharkiv, 4 Nauky Avenue

 
O. M. Kovalyova, Kharkiv National Medical University, Kharkiv, Ukraine

61022, Kharkiv, 4 Nauky Avenue

 

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How to Cite
Vizir, M. O., & Kovalyova, O. M. (1). ROLE OF NESFATIN-1 IN MAINTAINING CARBOHYDRATE HOMEOSTASIS IN HYPERTENSIVE PATIENTS. The Journal of V. N. Karazin Kharkiv National University, Series "Medicine", (32), 56-61. Retrieved from https://periodicals.karazin.ua/medicine/article/view/7828
Section
Clinical research