TYPE OF REACTION OF SIMPATO-VAGAL BALANCE IN A ACUTE FARM TEST WITH A METOPROLOL AND EFFICIENCY OF THERAPY OF HEART FAILURE
Abstract
The connection of efficiency of therapy by metoprolol (MT) with type of reactions of neurogumoral regulation on this drug in acute farm test (AFT) was investigated in 106 patients with a chronic heart failure. The type of reaction was determined by a heart rate variability method by change of sympathovagal balance (SVB) in AFT. Clinic and haemodinamic parameters and parameters of ultrasonic scanning of heart were studied prior to the beginning and upon termination of a stage of therapy by MT. By more significant the outcomes of therapy have appeared among the patients with decreasing of SVB.
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References
2. Метелица В.И. Справочник по клинической фармакологии сердечно-сосудистых лекарственных средств. - М.: Медпрактика. 1996.
3. Класифікація хронічної серцевої недостатності. Українське наукове товариство кардиологів. Ре-комендації з лікування хронічної серцевої недостатності. - К.: Четверта хвиля. 2002. 20 с.
4. CIBIS II Investigators and Committees. The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomized trial // Lancet. 1999. Vol. 353. P. 9-13.
5. Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of The European Society of Cardiology and The North American Society of Pacing and Electro-physiology (Membership of the Task Force listed in the Appendix). Europe Heart J. 1996. Vol. 17. P. 354-81.
6. McKelvie R, Yusuf S, Wiecek E et al. // European Society of Cardiology. 1997. Р. 42
7. MERIT-HF Study Group. Effects of controlled-release metoprolol on total mortality, hospitalization, and well-being in patients with heart failure. The Metoprolol CR/XL Randomized Intervention Trial in Con-gestive Heart Failure (MERIT-HF) // Lancet. 1999. Vol. 353. P. 2001-2007.
8. Packer M. // Eur Heart J. 1995. Vol. 16. Suppl. F. P.5-6.
9. Task Force for the diagnosis and treatment of chronic heart failure, European Society of Cardiology. Guidelines for the diagnosis and treatment of chronic heart failure // Europ. Heart J. 2001. Vol. 21. P. 1527-1560.
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