ANTHRACYCLINE-INDUCED CHANGES OF INTRACARDIAC HEMODYNAMICS

  • N.T. Vatutin
  • N.V. Kalinkina
  • T.S. Kiriyenko
  • E.V. Keting
  • V.V. Ridzhok
  • I.A. Saldadze
Keywords: anthracyclines, cumulative doze, cardiotoxicity, systolic and diastolic functions, left ventricle, echocardiography

Abstract

The article contains review of world literature and own observations concerning anthracycline cardiotoxicity. Changes in basic indices of systolic and diastolic cardiac functions induced by different cumulativedozes of anthracyclines are evaluated by modern methods of research. The question about safe dosage of anthracycline antibiotics is discussed. The comparative character of different representatives of this group ofmedicines according to their toxicity levels is described. The main purpose of the study is to find the mostsensitive criterion of myocardial damage after anthracycline therapy which can be revealed on the very early stages.

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How to Cite
Vatutin, N., Kalinkina, N., Kiriyenko, T., Keting, E., Ridzhok, V., & Saldadze, I. (1). ANTHRACYCLINE-INDUCED CHANGES OF INTRACARDIAC HEMODYNAMICS. The Journal of V. N. Karazin Kharkiv National University, Series "Medicine", (6), 14-20. Retrieved from https://periodicals.karazin.ua/medicine/article/view/7290
Issue
No. 6 (2003)
Section
Reviews

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