INFLUENCE OF METHOD OF PHYSICAL DISSECTION OF GASTRIC WALL ON THE PEROXIDATION

  • А.I. Thsivenko
Keywords: diathermy knife, ultrasonic scalpel, lipid peroxidation, large and small intestine

Abstract

The results of the intraoperative diathermy knife and ultrasonic scalpel use are presented in the paper. The indices of lipid peroxidation and chemiluminiscentia are explored in the experiment on Shinshilla rabbits and one hour later after the surgical procedure and on the third, seventh, fourteenth, thirtieth day of postoperative period. The gastrotomy performed with the help of a diathermy knife and ultrasonic scalpel leads to considerable activation of lipid peroxidation in tissues by means of free radical lipid oxidation and to reduction of garter tissues resistance for lipid peroxidation that becomes apparent in increase of tiobarbituric acid of active products concentration and chemiluminescence’s intensity evoked by Fe2+, and Н2О2.The ultrasonic scalpel application results in less apparent patologicprocess in the zone of action than the ultrasonic scalpel application that, doubtlessly, leads to more favorable postoperative period and reduces the risk of complications development.

Downloads

Download data is not yet available.

References

1. Андрианова М.Ю., Кукаева Е.А., Мильчаков В.И. и др. // Анестезиология и реаниматология. -2001. - № 2. - С. 33-35.

2. Арутюнян А.В., Дубинина Е.Е., Зыбина Н.Н. Методы оценки свободнорадикального окисления и антиоксидантной системы организма. Метод. Рек. СПб: ИКФ Фолиант. - 2000. - 104 с.

3. Владимиров Ю.А. // Биофизика. - 1987. - Т. 32(5). - С. 830-844.

4. Гальченко С.Є., Тининика Л.М., Сандомирський Б.П. // Мед. хімія. - 2005. - № 1. - С. 67-71.

5. Грищенко В.И., Никитченко Ю.В., Оченашко О.В. и др. // Бюл. эксперим. биол. и мед. - 2001. - Т. 132. - № 10. - С. 394-397.

6. Зозуля Ю. А., Барабой В. А., Сутковой Д. А. Свободнорадикальное окисление и антиоксидантная защита при патологии головного мозга. -М.:Знание-М. - 2000. - С. 70-78.

7. Рагимов Ч. Р., Касачанова Н. Ю., Тер-Асатуров Г. П. и др. // Стоматология.- 1991. - № 1.- С. 45-47.

8. Сахарова Т.С., Нiкiтченко Ю.В., Дзюба В.М. // Мед. хiмiя. - 2002. - Т. 4. - № 4. - С. 51-53.

9. Щербак В.А., Хышиктуев Б.С., Аксенова Т.А., и др. // Клиническая лабораторная диагностика. - 2005. - № 1. - С. 12-13.
How to Cite
ThsivenkoА. (1). INFLUENCE OF METHOD OF PHYSICAL DISSECTION OF GASTRIC WALL ON THE PEROXIDATION. The Journal of V. N. Karazin Kharkiv National University, Series "Medicine", (13), 67-71. Retrieved from https://periodicals.karazin.ua/medicine/article/view/7081
Issue
No. 13 (2006)
Section
Fundamental research

The Journal of V. N. Karazin Kharkiv National University, series Medicine has following copyright terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work, with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.