ANGIOTENSIN CONVERTING ENZYME INHIBITORS IN THE THERAPEUTIC CLINIC
Abstract
The clinical pharmacology of inhibitors of angiotensin converting enzyme (IACE) in the classification system of ATS is described. Clinical classification, pharmacokinetics and peculiarities of drugs of this group are submitted. Indications for use and features of use of ACE inhibitors in a therapeutic clinic are considered. The emphases of this group of drugs are placed for hypertension, heart failure and ischemic heart disease. The primary contraindications, emphases of interaction with other drugs, side effects and symptoms of overdose are given.
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http://medicusamicus.com/index.php?action=edpr-art_hyper_1
2. Каптоприл – первый ингибитор ангиотензин-превращающего фермента в лечении сердечно-сосудистых заболеваний: 40 лет / Д. В. Преображенский, Б. А. Сидоренко, И. С. Дедова, М. А. Бугримова, Е. В. Тарыкина // Учебные материалы Московской медицинской академии им. И. М. Сеченова: М. – 2005. – 14 с.
3. Сильная и слабая стороны одной гипотезы, или почемунужно «держать на уме» квинаприл [элек-тронный ресурс] / Яблучанский Н.И. // Medicus Amicus – 2007. Режим доступа к журн.:
http://www.medicusamicus.com/index.php?action=4x726-3e-13gx1
4. Shionoiri H. Pharmacokinetic drug interactions with ACE inhibitors. / H. Shionoiri // Clin Pharmacokinet. – 1993 Jul. – Vol. 25(1). – P. 20–58.
5. Новое – это хорошо забытое старое, или блокада ренин-ангиотензиновой системы «народным» ингибитором АПФ [электронный ресурс] / М.Н. Долженко // Медицина неотложных состояний – 2007. – № 3(10). – Режим доступа к журн.: http://urgent.mif-ua.com/archive/issue-108/
6. Сравнительная характеристика ингибиторов АПФ [электронный ресурс] / Корзун А.И., Кириллова М.В. // Экология человека – 2003. – № 2. – С. 16. – Режим доступа к журн.: http://www.medlinks.ru/article.php?sid=6018
7. Comparative impact of enalapril, candesartan or metoprolol alone or in combination on ventricular remodelling in patients with congestive heart failure / McKelvie R.S., Rouleau J.L., White M. [et al.] // Eur Heart J. – 2003. – № 24. – Р. 1727–1734.
8. Клиническая кардиология. Руководство для врачей. Пер. с англ. / [Александер Р.В., Шлант Р.К., Фастер В. и др.]; под ред. Сонненблика Э.Г. – [2-е издание] – М.: СПб: «Издательство БИНОМ» - «Невский диалект», 2002. – 672 с., ил.
9. Национальные Рекомендации ВНОК И ОССН по диагностике и лечению ХСН/ Мареев В. Ю., Агеев Ф. Т., Арутюнов Г. П. и др. – [второй пересмотр] // Журнал Сердечная Недостаточность. – 2006. – Том 8, № 2. – С. 1–35.
10. The CONSENSUS Trial Study Group. Effects of enalapril on mortality in severe congestive heart failure: results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS) // N Engl J Med. – 1987 – Vol. 316. – Р. 1429–1435.
11. The SOLVD investigators- Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions // N Engl. J Med. – 1992. – Vol. 327. – Р. 685–691.
12. The SOLVD investigators - Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure // N Engl. J Med. –1991. – Vol. 325. – Р. 293–302
13. Garg R., Yusuf S., for the Collaborative Group on ACE Inhibitor Trials. Overview of randomized trials of angiotensin- converting enzyme inhibitors on mortality and morbidity in patients with heart failure // JAMA. – 1995. – Vol. 273(18). – Р. 1450–1456.
14. Cleland J.G., Tendera M., Adamus J. et al. PEP-CHF Investigators The perindopril in elderly people with chronic heart failure (PEP-CHF) study Eur Heart J. – 2006. – Vol. 27(19). – 2338–2345.
15. A comparison of enalapril with hydralazine–isosorbide dinitrate in the treatment of chronic congestive heart failure / Cohn J.N., Johnson G., Ziesche S. [et al.] // N Engl J. Med. 1991; Vol. 325: 303–310.
16. Long-term ACE-inhibitor therapy in heart failure or left-ventricular dysfunction: a systemic overview of data from individual patients / Flather M.D., Yusuf S., Kober L. [et al.] // Lancet. – 2000. – Vol. 355. – Р. 1575–1581.
17. Ambrosioni E., Borghi C., Magnani Ç for the survival of myocardial infarction long term evaluation (SMILE) Study Investigators. The effect of the angiotensin-converting-enzyme inhibitor on mortality and morbidity after anterior myocardial infarction // N Engt J Med. – 1995. – Vol. 332. – Р. 80–85.
18. ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction- executive summary: a report of the ACC/AHA Task Force on Practice Guidelines (Committee to Revise the 1999 Guidelines on the Management of Patients With Acute Myocardial Infarction / Antman E.M., Anbe D.T., Armstrong P.W. [et al.] // J. Am Coll Cardiol. – 2004. – Vol. 44. – Р. 671–719.
19. Кукес В.Г. Клиническая фармакология / В.Г. Кукес. – [2 изд.] – М.: ГЭОТАР МЕДИЦИНА, 1999. – 528 с.
20. Gomez H.J. Enalapril: a review of human pharmacology / H.J. Gomez, V.J. Cirillo, J.D. Irvin // Drugs. – 1985. – 30 Suppl 1. – Р. 13–24.
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