CURRENCY AND OUTCOMES IN ARTERIAL HYPERTENSION PATIENTS WITH DIFFERENT TYPES OF SYSTOLIC ARTERIAL BLOOD PRESSURE ORTHOSTATIC REACTIONS
Keywords:
systolic blood pressure, orthostatic reactions, arterial hypertension
Abstract
Peculiarities of currency and outcomes in arterial hypertension (AH) patients with hypotensive, isotensive and hypertensive orthostatic reactions (OR) of systolic arterial blood pressure (SBP) were studied in the follow up of 113 AH patients, age 64,73±6,42 years. 44 males and 69 females. According to the SBP in orthostatic test patients were divided into 3 groups: group 1 – hypotensive OR, group 2 – isotensive OR and group 3 – hypertensive OR. AH grades and stages frequencies, HF functional class after 4 years of treatment, and the severity and frequency of adverse cardiovascular events and outcomes were identified. Data was processed by the variation statistics methods. It was found that the less severe currency of AH is seen in hypertensive type, more severe in hypotensive type, and the most severe in isotensive type of SBP orthostatic reactions. In general quantity of adverse events and outcomes is more frequently seen in isotensive type of SBP OR – 46%, is less frequently seen in hypertensive type – 18%. In AH patients it is necessary to pay special attention not only to the BP control, but also to the optimization of SBP orthostatic reactions.Downloads
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References
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3. Dobkin Bruce. Orthostatic hypotension as a risk factor for symptomatic occlusive cerebrovascular disease // NEUROLOGY. – 1999. – Р. 39-30.
4. Eigenbrodt M. L. Orthostatic hypotension as a risk factor for stroke: the atherosclerosis risk in commun-ities (ARIC) study, 1987-1996 / Eigenbrodt M. L. et al. // Stroke. – 2000. –Vol. 10, № 3. – P. 307-313.
5. European Society of Hypertension 2003 – European Society of Cardiology guidelines for the management of arterial hypertension // Journal of Hypertension. – 2003. – № 21. – Р. 1011-1053.
6. Gangnon R. Sequential Monitoring of Multiple Endpoints in Clinical Trials. Statistical Data Analysis Cen-ter Department of Biostatistics and Medical Informatics University of Wisconsin Madison / Roecker E. and Cook T. // Wisconsin, May 3, – 1999.
7. Hansson L. Randomised trial of effects of calcium antagonists compared with diuretics and beta-blockers on cardiovascular morbidity and mortality in hypertension: the Nordic Diltiazem (NORDIL) study / Hansson L. – 2000. – 356 (9227) : 359-65.
8. Kaplan N. Clinical Trials for Hypertension. Expectations Fulfilled and Unfulfilled. Hypertension / Kaplan N. – 2007. – № 49. – Р. 257.
9. Kazuomi Kario. U-curve relationship between orthostatic blood pressure change and silent cerebrovascu-lar disease in elderly hypertensives. [Orthostatic hypertension as a new cardiovascular risk factor in clini-cal study]. /Kazuo Eguchi, Satoshi Hoshide, Yoko Hoshide, Yuji Umeda, Takeshi Mitsuhashi and Ka-zuyuki Shimada. – 2002. – Р. 9-
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12. M. Sahni, D. T. Lowenthal, J. Meuleman // International Urology and Nephrology. – 2005. – Vol. 37. – Р. 669-674.
13. Sartori M. Orthostatic Hypotension and Supine Hypertension in Primary Autonomic Failure. Hypertension. / Sartori M. – 2005. – № 45. – Р. 18.
14. Тeik Ong Hean. Cardiovascular outcomes in the comparative hypertension drug trials: more consensus than controversy // Singapore Med J. – 2008. – № 49 (8). – Р. 599.
15. Timothy C. Hain et al. // Orthostatic hypotension. Proceedings of National Institute of Health. – 2003. – Vol. 5. – Р. 42.
How to Cite
Iegorova, A. Y., Garkaviy, P. O., & Yablucnasky, M. I. (1). CURRENCY AND OUTCOMES IN ARTERIAL HYPERTENSION PATIENTS WITH DIFFERENT TYPES OF SYSTOLIC ARTERIAL BLOOD PRESSURE ORTHOSTATIC REACTIONS. The Journal of V. N. Karazin Kharkiv National University, Series "Medicine", (20), 28-32. Retrieved from https://periodicals.karazin.ua/medicine/article/view/6908
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