The main clinical manifestations of nervous-mental complications in toxoplasmic infection and their non-specific prevention
Abstract
The article is dedicated to topical problems of prevention of neuropsychiatric complications of socially significant parasitosis – toxoplasmosis in Ukraine. The clinical features of the course of chronic toxoplasmosis, changes in the bioelectrical activity of the brain in patients with toxoplasmosis in the acute stage are described. In order to objectify the assessment of the nature of damage to the nervous system of patients, an electroencephalographic (EEG) study was performed with visual assessment and computer processing of the results. Changes in the infrastructure of correlations between clinical and EEG parameters in patients with chronic toxoplasmosis in the acute stage before treatment are described. The main solutions for non-specific prevention of neuropsychiatric complications in this parasite are presented. The significance of the study of the parameters of bioelectrical activity of the brain in patients with toxoplasmosis, which can be used as auxiliary prognostic criteria, is substantiated. The main measures for the prevention of congenital toxoplasmosis, which is dangerous, especially for newborns and people with immunodeficiency, are outlined. The above is a necessary basis for improving the system of epidemiological monitoring for the spread of toxoplasmosis in Ukraine, and strengthening control by state institutions to prevent parasitological pollution, as well as the creation of a National Program for surveillance of parasitic infestations, to control the spread of parasitosis, and warn of severe consequences for the health of the infected
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References
Aver’janova, EL. Clinical and immunological characteristics of chronic toxoplasmosis with damage to the organ of vision: dissertation. 2006;143. Available from: http://www.dissercat.com
Golubovskaja, OA, editor, Andrejchin, MA, Shkurba, AV. Infectious diseases: textbook. K. Medicine: 783. 2014. Available from: http://www.ec.elibumsa.pl.ua › cgi-bin › cgiirbis_64 › b =red 20
Sergiev, VP. Human parasitic diseases (protozoses and helminthiases): a guide for doctors StP.; Foliant. 2016: 640. URL: Available from: https://www.books-up.ru/ru/book/parazitarnye-bolezni-cheloveka-5229792/ [cited 06.10.2020]
Morozov, EN, Litvinov, SK, Zhirenkina, EN. About the concept of elimination of infectious diseases. Epidemiology and infectious diseases. 2016; (2): 68–73. Available from: http://www.rsml.med.by
Morita, A. Clinical and Laboratory Diagnosis of Central Nervous System Infections. Brain Nerve. 2015; Jul; 67 (7): 777–85. https://doi.org/10.11477/mf.1416200218.PMID: 26160808 Japanese
Vozianova, ZhI. Infectious and parasitic diseases. K.: Zdorov’ya. 2002;(3):285–315. Available from: http://www.booksmed.com
Haitov RM, Alekseev LP. Immunogenetics and biosafety. M.: LLC «Mittel Press». 2014: 232. Available from: http://www.irbis.rmapo.ru › cgi-bin › cgiirbis_64
Zhirmunskaja EA. Central mechanisms of afferentation in humans. M.: Medicine. 1997: 272 с. Available from: http://www.cerebral-asymmetry.narod.ru
Garkavi, LH, Kvakina, EB, Ukolova, MA. Adaptive reactions and resistance of the organism. R.: 3rd edition of Rostov University. 2000: 224. Available from: http://www.rep.bsmu.by
Kanjilal, S, Cho, TA, Piantadosi, A. Semin. Diagnostic Testing in Central Nervous System Infection. Neurol. 2019, Jun; 39 (3): 297–311. https://doi.org/10.1055/s-0039-1688441
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