The main clinical manifestations of nervous-mental complications in toxoplasmic infection and their non-specific prevention

  • Oksana Bobrova MD, PhD, Assistant professor of department of hygiene and social medicine, V. N. Karazin Kharkiv National University, School of Medicine https://orcid.org/0000-0002-5953-1071
  • Natalia Mikhanovska MD, PhD, Professor of department of hygiene and social medicine, V. N. Karazin Kharkiv National University; School of Medicine https://orcid.org/0000-0001-7154-1179
  • Krystyna Kryvonos MD, PhD, Assistant professor of department of hygiene and social medicine; V. N. Karazin Kharkiv National University; School of Medicine https://orcid.org/0000-0003-0302-0835
Keywords: parasitosis, neuropsychiatric complications, toxoplasmosis, prevention

Abstract

The article is dedicated to topical problems of prevention of neuropsychiatric complications of socially significant parasitosis – toxoplasmosis in Ukraine. The clinical features of the course of chronic toxoplasmosis, changes in the bioelectrical activity of the brain in patients with toxoplasmosis in the acute stage are described. In order to objectify the assessment of the nature of damage to the nervous system of patients, an electroencephalographic (EEG) study was performed with visual assessment and computer processing of the results. Changes in the infrastructure of correlations between clinical and EEG parameters in patients with chronic toxoplasmosis in the acute stage before treatment are described. The main solutions for non-specific prevention of neuropsychiatric complications in this parasite are presented. The significance of the study of the parameters of bioelectrical activity of the brain in patients with toxoplasmosis, which can be used as auxiliary prognostic criteria, is substantiated. The main measures for the prevention of congenital toxoplasmosis, which is dangerous, especially for newborns and people with immunodeficiency, are outlined. The above is a necessary basis for improving the system of epidemiological monitoring for the spread of toxoplasmosis in Ukraine, and strengthening control by state institutions to prevent parasitological pollution, as well as the creation of a National Program for surveillance of parasitic infestations, to control the spread of parasitosis, and warn of severe consequences for the health of the infected

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Author Biographies

Oksana Bobrova, MD, PhD, Assistant professor of department of hygiene and social medicine, V. N. Karazin Kharkiv National University, School of Medicine

6, Svobody Sq., Kharkiv, Ukraine, 61022;

infectious disease doctor, Kharkov Regional Hospital of Infectious Diseases

Natalia Mikhanovska, MD, PhD, Professor of department of hygiene and social medicine, V. N. Karazin Kharkiv National University; School of Medicine

6, Svobody Sq., Kharkiv, Ukraine, 61022;

Leading Researcher of Department of Psychiatry State Institution «Institute of Children and Adolescent Health Сare Academy of Medical Sciences of Ukraine»

Krystyna Kryvonos, MD, PhD, Assistant professor of department of hygiene and social medicine; V. N. Karazin Kharkiv National University; School of Medicine

6, Svobody Sq., Kharkiv, Ukraine, 61022;

Director of Kharkov Municipal Enterprise «Sanepidservice»

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Published
2020-12-08
How to Cite
Bobrova, O., Mikhanovska, N., & Kryvonos, K. (2020). The main clinical manifestations of nervous-mental complications in toxoplasmic infection and their non-specific prevention. The Journal of V. N. Karazin Kharkiv National University, Series "Medicine", (40), 13-22. https://doi.org/10.26565/2313-6693-2020-40-02