Cardiolipin effect on the lipid bilayer structure: pyrene excimerization study
Keywords:
liposomes, pyrene excimer formation, cardiolipin, lipid bilayer structure, free volumeAbstract
The influence of cardiolipin (CL) on the structural state of model membranes has been examined using the pyrene epimerization technique. The excimer-to-monomer ratio decreased by 11 % as CL content increased from 0 to 10 mol % suggesting that CL can induce bilayer condensation. At higher CL concentrations (20 and 40 mol %) excimer-to-monomer ratio tended to increase is indicative of the reduced lipid packing density. The biological role of CL is discussed.
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Published
2005-06-06
Issue
Section
Methods of biophysical investigations
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How to Cite
Cardiolipin effect on the lipid bilayer structure: pyrene excimerization study. (2005). Biophysical Bulletin, 1(15), 104-107. https://periodicals.karazin.ua/biophysvisnyk/article/view/18288
