Fluorescent probe study of model phosphatidylcholine/cardiolipin membranes
Keywords:
cardiolipin, liposomes, fluorescent probes, bilayer structureAbstract
The effect of negatively charged phospholipid cardiolipin (CL) on the structural state of phosphatidylcholine (PC) model membranes was studied using fluorescent probes 4-(n-dimethylaminostyryl)-1-methylpyridinium (DSM) and 3 methoxybenzanthrone (MBA). Electrostatic and non-electrostatic contributions to the stabilization of DSM-lipid complexes were evaluated. MBA bilayer distribution was found to change on increasing CL content from 5 to 10 mol % suggesting that incorporation of small amounts of CL into PC bilayer is followed by pronounced modification of the membrane structure
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Published
2005-06-06
Issue
Section
Methods of biophysical investigations
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How to Cite
Fluorescent probe study of model phosphatidylcholine/cardiolipin membranes. (2005). Biophysical Bulletin, 1(15), 108-110. https://periodicals.karazin.ua/biophysvisnyk/article/view/18290
